Comprehensive temporal information detection from clinical text: medical events, time, and TLINK identification.

Background: Temporal information detection systems have been developed by the Mayo Clinic for the 2012 i2b2 Natural Language Processing Challenge.Objective: To construct automated systems for EVENT/TIMEX3 extraction and temporal link (TLINK) identification from clinical text.Materials and Methods: T...

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Published in:Journal of the American Medical Informatics Association Vol. 20; no. 5; pp. 836 - 843
Main Authors: Sohn, Sunghwan, Wagholikar, Kavishwar B, Li, Dingcheng, Jonnalagadda, Siddhartha R, Tao, Cui, Komandur Elayavilli, Ravikumar, Liu, Hongfang
Format: research Journal Article
Published: Oxford University Press / USA Sep2013
Online Access:View this record in EBSCOhost
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        10.1136/amiajnl-2013-001622
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        atl: Comprehensive temporal information detection from clinical text: medical events, time, and TLINK identification.
      aug:
        au:
          Sohn, Sunghwan
          Wagholikar, Kavishwar B
          Li, Dingcheng
          Jonnalagadda, Siddhartha R
          Tao, Cui
          Komandur Elayavilli, Ravikumar
          Liu, Hongfang
        affil: Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota, USA.
      sug:
        subj:
          Artificial Intelligence
          Electronic Health Records
          Information Retrieval Methods
          Natural Language Processing
          Patient Discharge
          Human
          Time
      ab: Background: Temporal information detection systems have been developed by the Mayo Clinic for the 2012 i2b2 Natural Language Processing Challenge.Objective: To construct automated systems for EVENT/TIMEX3 extraction and temporal link (TLINK) identification from clinical text.Materials and Methods: The i2b2 organizers provided 190 annotated discharge summaries as the training set and 120 discharge summaries as the test set. Our Event system used a conditional random field classifier with a variety of features including lexical information, natural language elements, and medical ontology. The TIMEX3 system employed a rule-based method using regular expression pattern match and systematic reasoning to determine normalized values. The TLINK system employed both rule-based reasoning and machine learning. All three systems were built in an Apache Unstructured Information Management Architecture framework.Results: Our TIMEX3 system performed the best (F-measure of 0.900, value accuracy 0.731) among the challenge teams. The Event system produced an F-measure of 0.870, and the TLINK system an F-measure of 0.537.Conclusions: Our TIMEX3 system demonstrated good capability of regular expression rules to extract and normalize time information. Event and TLINK machine learning systems required well-defined feature sets to perform well. We could also leverage expert knowledge as part of the machine learning features to further improve TLINK identification performance.
      pubtype: Academic Journal
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        Journal Article
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    language: English
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