From the mediterranean to the sea of Japan: the transcontinental odyssey of autoinflammatory diseases.

Autoinflammatory diseases are comprehensively caused by aberrant production of proinflammatory cytokines and are revealed by cyclically and spontaneously occurring inflammatory events. Over the last decade, there has been a revolution in the understanding of periodic fever syndromes, cryopyrinopathi...

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Publicado en:BioMed Research International Vol. 2013; pp. 485103 - 485104
Autores principales: Rigante, Donato, Frediani, Bruno, Galeazzi, Mauro, Cantarini, Luca
Formato: Journal Article
Publicado: Wiley-Blackwell 2013
Acceso en línea:Ver este registro en EBSCOhost
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        atl: From the mediterranean to the sea of Japan: the transcontinental odyssey of autoinflammatory diseases.
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          Rigante, Donato
          Frediani, Bruno
          Galeazzi, Mauro
          Cantarini, Luca
        affil: Institute of Pediatrics, Università Cattolica Sacro Cuore, Largo A. Gemelli 8, 00168 Rome, Italy.
      sug:
        subj:
          Autoimmune Diseases Epidemiology
          Autoimmune Diseases
          Disease Outbreaks
          Disease Susceptibility Epidemiology
          Disease Susceptibility
          Inflammation Epidemiology
          Inflammation
          Incidence
          Japan
          Mediterranean Region
          Risk Factors
      ab: Autoinflammatory diseases are comprehensively caused by aberrant production of proinflammatory cytokines and are revealed by cyclically and spontaneously occurring inflammatory events. Over the last decade, there has been a revolution in the understanding of periodic fever syndromes, cryopyrinopathies, and skin disorders with pyogenic, granulomatous, or dystrophic features, which have been recognized across different countries spanning from the Mediterranean basin to the Japanese archipelago. Many children and adults with autoinflammatory diseases continue to elude diagnosis, and the diagnostic delay of many years puts these patients at risk of long-term severe complications, such as amyloidosis. Any hint of suspicion of autoinflammatory disease thus needs to be highlighted in various medical specialties, and this review examines their frequencies around the world, trying to match them with geographic location, ethnic and genetic data, in an attempt to realize a geoepidemiologic map for most of these conditions.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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