Biomedical Applications of Fermenticin HV6b Isolated from Lactobacillus fermentum HV6b MTCC10770.
Fermenticin HV6b is a class IIa antimicrobial peptide produced by Lactobacillus fermentum HV6b MTCC 10770 isolated from human vaginal ecosystem. It shows growth inhibition of a wide range of opportunistic pathogens of humans, for example, Bacteroides, Gardnerella vaginalis, Mobiluncus, Staphylococci...
| Publicado en: | BioMed Research International Vol. 2013; pp. 168438 - 168439 |
|---|---|
| Autores principales: | , , , , |
| Formato: | Journal Article |
| Publicado: |
Wiley-Blackwell
2013
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104090722&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104090722 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 2013 vid: 2013 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104090722 2012240499 NLM23984320 PMC3745898 104090722 ppf: 168438 ppct: 1 formats: fmt: @attributes: type: P tig: atl: Biomedical Applications of Fermenticin HV6b Isolated from Lactobacillus fermentum HV6b MTCC10770. aug: au: Kaur, Baljinder Balgir, Praveen P Mittu, Bharti Kumar, Balvir Garg, Neena affil: Department of Biotechnology, Punjabi University, Patiala, Punjab 147002, India. sug: subj: Antiinfective Agents Pharmacodynamics Antineoplastic Agents Pharmacodynamics Proteins Pharmacodynamics Lactobacillus Animals Antiinfective Agents Bacteria Drug Effects Proteins Cell Death Drug Effects Cell Line Cell Physiology Drug Effects DNA Drug Effects Drug Screening Assays, Antitumor Genome, Human Male Mice Microbial Culture and Sensitivity Tests Sperm Motility Drug Effects Spermatozoa Spermatozoa Drug Effects Male ab: Fermenticin HV6b is a class IIa antimicrobial peptide produced by Lactobacillus fermentum HV6b MTCC 10770 isolated from human vaginal ecosystem. It shows growth inhibition of a wide range of opportunistic pathogens of humans, for example, Bacteroides, Gardnerella vaginalis, Mobiluncus, Staphylococci, and Streptococci, associated with bacterial vaginosis in humans. It does possess an impressive sperm immobilization and spermicidal activity tested against human sperms which makes it an attractive proposition for formulating antibacterial vaginosis and contraceptive products. Apart from this, in vitro studies conducted against four different tissue models have indicated its potential to be used as a component of anticancerous drug therapy as it is reported to induce apoptosis in cancerous cells. This information could be integrated in future studies focusing on in vivo assessment of anticancerous activity of lactic acid bacterial toxins or bacteriocins. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|