Effect of boron addition on the thermal, degradation, and cytocompatibility properties of phosphate-based glasses.
In this study eight different phosphate-based glass compositions were prepared by melt-quenching: four in the (P2O5)45-(CaO)16-(Na2O)15-x-(MgO)24-(B2O3)x system and four in the system (P2O50)5-(CaO)16-(Na2O)10-x-(MgO)24-(B2O3)x, where x = 0,1,5 and10mol%. The effect ofB2O3 addition on the thermal pr...
| Publicado en: | BioMed Research International Vol. 2013; pp. 902427 - 902428 |
|---|---|
| Autores principales: | , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
2013
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104091342&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104091342 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 2013 vid: 2013 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104091342 104091342 2012243978 NLM23991425 PMC3749540 104091342 ppf: 902427 ppct: 1 formats: fmt: @attributes: type: P tig: atl: Effect of boron addition on the thermal, degradation, and cytocompatibility properties of phosphate-based glasses. aug: au: Sharmin, Nusrat Hasan, Muhammad S Parsons, Andrew J Furniss, David Scotchford, Colin A Ahmed, Ifty Rudd, Chris D affil: Division of Materials, Mechanics and Structures, Faculty of Engineering, University of Nottingham, Nottingham NG7 2RD, UK. sug: subj: Biocompatible Materials Biocompatible Materials Pharmacodynamics Connective Tissue Cells Drug Effects Elements Glass Phosphates Phosphates Pharmacodynamics Animal Studies Cell Line Cell Physiology Drug Effects Connective Tissue Cells Materials Testing Mice Temperature ab: In this study eight different phosphate-based glass compositions were prepared by melt-quenching: four in the (P2O5)45-(CaO)16-(Na2O)15-x-(MgO)24-(B2O3)x system and four in the system (P2O50)5-(CaO)16-(Na2O)10-x-(MgO)24-(B2O3)x, where x = 0,1,5 and10mol%. The effect ofB2O3 addition on the thermal properties, density, molar volume, dissolution rates, and cytocompatibility were studied for both glass systems. Addition of B2O3 increased the glass transition (Tg), crystallisation (Tc), melting (Tm), Liquidus (TL) and dilatometric softening (Td) temperature and molar volume (Vm). The thermal expansion coefficient (a.) and density (p) were seen to decrease. An assessment of the thermal stability of the glasses was made in terms of their processing window (crystallisation onset, Tcons minus glass transition temperature, Tg), and an increase in the processing window was observed with increasing B2O2 content. Degradation studies of the glasses revealed that the rates decreased with increasing B2O3 content and a decrease in degradation rates was also observed as the P2O5 content reduced from 50 to 45mol%. MG63 osteoblast-like cells cultured in direct contact with the glass samples for 14 days revealed comparative data to the positive control for the cell metabolic activity, proliferation, ALP activity, and morphology for glasses containing up to 5 mol% of B2 O3. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|