Laparoscopic and robotic radical prostatectomy outcomes in obese and extremely obese men.

Objective: To evaluate the operative and pathologic outcomes of laparoscopic radical prostatectomy and robot-assisted radical prostatectomy in men with progressive changes in body mass index (BMI) category.Materials and Methods: A single-surgeon series of 1023 laparoscopic radical prostatectomy and...

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Publicado en:Urology Vol. 82; no. 3; pp. 600 - 606
Autores principales: Sundi, Debasish, Reese, Adam C, Mettee, Lynda Z, Trock, Bruce J, Pavlovich, Christian P
Formato: research Journal Article
Publicado: Elsevier B.V. Sep2013
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2013
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      pub: Elsevier B.V.
      place: New York, New York
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        10.1016/j.urology.2013.05.013
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        atl: Laparoscopic and robotic radical prostatectomy outcomes in obese and extremely obese men.
      aug:
        au:
          Sundi, Debasish
          Reese, Adam C
          Mettee, Lynda Z
          Trock, Bruce J
          Pavlovich, Christian P
        affil: James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD. Electronic address: dsundi1@jhmi.edu.
      sug:
        subj:
          Body Mass Index
          Lymph Node Excision
          Obesity Complications
          Prostatectomy Methods
          Prostatic Neoplasms Pathology
          Prostatic Neoplasms Surgery
          Blood Loss, Surgical
          Human
          Laparoscopy Adverse Effects
          Length of Stay
          Male
          Middle Age
          Neoplasm Staging
          Neoplastic Processes
          Obesity, Morbid Complications
          Therapeutics
          Pelvis
          Prostate-Specific Antigen Blood
          Prostatectomy Adverse Effects
          Prostatic Neoplasms Blood
          Retrospective Design
          Robotics
          Treatment Outcomes
          Middle Aged: 45-64 years
          Male
      ab: Objective: To evaluate the operative and pathologic outcomes of laparoscopic radical prostatectomy and robot-assisted radical prostatectomy in men with progressive changes in body mass index (BMI) category.Materials and Methods: A single-surgeon series of 1023 laparoscopic radical prostatectomy and robot-assisted radical prostatectomy (mostly extraperitoneal) patients was considered. Of these patients, 987 were evaluable. Results were stratified by the World Health Organization BMI category. Multivariate linear and logistic regression analysis was used to model the operating time, length of stay, positive surgical margins, and noncurable cancer.Results: Of the 987 patients, 563 (57%) were overweight and 193 (19.6%) were obese. Of the 193 obese patients, 152 (15.4%) had a BMI of 30 to <35 kg/m(2) (class I obesity), 28 (2.8%) a BMI of 35 to <40 kg/m(2) (class II), and 13 (1.3%) a BMI of ≥40 kg/m(2) (class III). No differences were found in the estimated blood loss, complications, PSM, pathologic stage, or biochemical recurrence across the BMI categories (6-month median follow-up). However, pelvic lymph node dissection was more commonly omitted and the nerve-sparing score was inferior in the obese men. On multivariate analysis, a higher BMI was a significant predictor of a longer operating time.Conclusion: Obese men can safely undergo laparoscopic radical prostatectomy or robot-assisted radical prostatectomy, although the ability to perform excellent nerve sparing appears to decrease with increasing obesity. Nevertheless, obese men can expect perioperative and early oncologic outcomes comparable to those of normal weight men without an increased risk of perioperative complications.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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