Stereotactic body radiotherapy as an alternative to brachytherapy in gynecologic cancer.
Introduction. Brachytherapy plays a key role in the treatment of many gynecologic cancers. However, some patients are unable to tolerate brachytherapy for medical or other reasons. For these patients, stereotactic body radiotherapy (SBRT) offers an alternative form of treatment. Methods. Retrospecti...
| Publicado en: | BioMed Research International Vol. 2013; pp. 898953 - 898954 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Wiley-Blackwell
2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104092207&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104092207 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 2013 vid: 2013 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104092207 104092207 2012245724 NLM24000329 PMC3755408 104092207 ppf: 898953 ppct: 1 formats: fmt: @attributes: type: P tig: atl: Stereotactic body radiotherapy as an alternative to brachytherapy in gynecologic cancer. aug: au: Kubicek, Gregory J Xue, Jinyu Xu, Qianyi Asbell, Sucha O Hughes, Leslie Kramer, Noel Youssef, Ashraf Chen, Yan Aikens, James Saul, Howard Pahlajani, Niraj Lacouture, Tamara affil: Department of Radiation Oncology, Cooper University Hospital, One Cooper Plaza, Camden, NJ 08103, USA. sug: subj: Brachytherapy Methods Genital Neoplasms, Female Therapy Radiosurgery Methods Aged Aged, 80 and Over Female Human Middle Age Radiation Dosage Retrospective Design Treatment Outcomes Aged: 65+ years Aged, 80 & over Middle Aged: 45-64 years Female ab: Introduction. Brachytherapy plays a key role in the treatment of many gynecologic cancers. However, some patients are unable to tolerate brachytherapy for medical or other reasons. For these patients, stereotactic body radiotherapy (SBRT) offers an alternative form of treatment. Methods. Retrospective review of patients prospectively collected on SBRT database is conducted. A total of 11 gynecologic patients who could not have brachytherapy received SBRT for treatment of their malignancies. Five patients have been candidates for interstitial brachytherapy, and six have required tandem and ovoid brachytherapy. Median SBRT dose was 25 Gy in five fractions. Results. At last followup, eight patients were alive, and three patients had died of progressive disease. One patient had a local recurrence. Median followup for surviving patients was 420 days (median followup for all patients was 120 days). Two patients had acute toxicity (G2 dysuria and G2 GI), and one patient had late toxicity (G3 GI, rectal bleeding requiring cauterization). Conclusions. Our data show acceptable toxicity and outcome for gynecologic patients treated with SBRT who were unable to receive a brachytherapy boost. This treatment modality should be further evaluated in a phase II study. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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