Cryptococcus gattii infections in multiple states outside the US Pacific Northwest.
Clonal VGII subtypes (outbreak strains) of Cryptococcus gattii have caused an outbreak in the US Pacific Northwest since 2004. Outbreak-associated infections occur equally in male and female patients (median age 56 years) and usually cause pulmonary disease in persons with underlying medical conditi...
| Publicado en: | Emerging Infectious Diseases Vol. 19; no. 10; pp. 1621 - 1628 |
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| Autores principales: | , , , , , , , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Centers for Disease Control & Prevention (CDC)
Oct2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104097178&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104097178 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10806040 EFD jtl: Emerging Infectious Diseases issn: 10806040 maglogo: N pubinfo: dt: Oct2013 vid: 19 iid: 10 pid: 1493 pub: Centers for Disease Control & Prevention (CDC) place: Atlanta, Georgia artinfo: ui: 104097178 NLM24050410 2012304145 10.3201/eid1910.130441 NLM24050410 PMC3810751 104097178 ppf: 1621 ppct: 7 formats: tig: atl: Cryptococcus gattii infections in multiple states outside the US Pacific Northwest. aug: au: Harris, Julie R Lockhart, Shawn R Sondermeyer, Gail Vugia, Duc J Crist, Matthew B D'Angelo, Melissa Tobin Sellers, Brenda Franco-Paredes, Carlos Makvandi, Monear Smelser, Chad Greene, John Stanek, Danielle Signs, Kimberly Nett, Randall J Chiller, Tom Park, Benjamin J sug: subj: Cryptococcosis Mortality Cryptococcus Immunology Lung Diseases, Fungal Mortality Adolescence Adult Aged Aged, 80 and Over Cryptococcosis Immunology Cryptococcosis Microbiology Cryptococcus Disease Outbreaks Female Genotype Lung Diseases, Fungal Immunology Lung Diseases, Fungal Microbiology Male Middle Age Evolution United States Young Adult Adolescent: 13-18 years Adult: 19-44 years Aged: 65+ years Aged, 80 & over Middle Aged: 45-64 years Female Male ab: Clonal VGII subtypes (outbreak strains) of Cryptococcus gattii have caused an outbreak in the US Pacific Northwest since 2004. Outbreak-associated infections occur equally in male and female patients (median age 56 years) and usually cause pulmonary disease in persons with underlying medical conditions. Since 2009, a total of 25 C. gattii infections, 23 (92%) caused by non-outbreak strain C. gattii, have been reported from 8 non-Pacific Northwest states. Sixteen (64%) patients were previously healthy, and 21 (84%) were male; median age was 43 years (range 15-83 years). Ten patients who provided information reported no past-year travel to areas where C. gattii is known to be endemic. Nineteen (76%) patients had central nervous system infections; 6 (24%) died. C. gattii infection in persons without exposure to known disease-endemic areas suggests possible endemicity in the United States outside the outbreak-affected region; these infections appear to differ in clinical and demographic characteristics from outbreak-associated C. gattii. Clinicians outside the outbreak-affected areas should be aware of locally acquired C. gattii infection and its varied signs and symptoms. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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