Primary immunodeficiency diseases at reference and high-specialty hospitals in the state of guanajuato, Mexico.
Background. In general, primary immunodeficiency diseases (PIDs) are underdiagnosed in most countries. The objective of this study was to describe the frequency and clinical spectrum of PID in the most important tertiary hospitals in our region. Methods. An observational, cross-sectional, with retro...
| Publicado en: | BioMed Research International Vol. 2013; pp. 187254 - 187255 |
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| Autores principales: | , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Wiley-Blackwell
2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104098885&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104098885 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 2013 vid: 2013 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104098885 104098885 2012313460 NLM24073395 PMC3773974 104098885 ppf: 187254 ppct: 1 formats: fmt: @attributes: type: P tig: atl: Primary immunodeficiency diseases at reference and high-specialty hospitals in the state of guanajuato, Mexico. aug: au: Guaní-Guerra, Eduardo García-Ramírez, Ulises Noel Jiménez-Romero, Ana Isabel Velázquez-Avalos, José Manuel Gallardo-Martínez, Gabriela Mendoza-Espinoza, Francisco-Javier affil: Departamento de Inmunología, Hospital Regional de Alta Especialidad del Bajío, Boulevard Milenio 130 San Carlos La Roncha, 37660 León, GTO, Mexico. sug: subj: Hospitals Statistics and Numerical Data Immunologic Deficiency Syndromes Epidemiology Adolescence Child Female Human Immunologic Deficiency Syndromes Etiology Immunologic Deficiency Syndromes Pathology Male Mexico Adolescent: 13-18 years Child: 6-12 years Female Male ab: Background. In general, primary immunodeficiency diseases (PIDs) are underdiagnosed in most countries. The objective of this study was to describe the frequency and clinical spectrum of PID in the most important tertiary hospitals in our region. Methods. An observational, cross-sectional, with retrospective chart, review study was conducted. A total of 26 patients were included and grouped according to the updated classification of PIDs. Results. PIDs spectra were as follows: predominantly antibody deficiency diseases were the most common category (65.38%), followed by other well-defined immunodeficiency syndromes (11.55%), congenital defects of phagocyte number and/or function (7.69%), complement deficiencies (3.85%), combined T- and B-cell immunodeficiencies (3.85%), and defects in innate immunity (3.85%). The mean time elapsed from the onset of symptoms to the reference and diagnosis by a tertiary hospital was of 4.65 ± 6.95 years. Conclusions. Predominant antibody deficiency disease was the most common group of PIDs, agreeing with international reports. Awareness of underdiagnosis by physicians is crucial for a prompt diagnosis and treatment, which in turn should improve the quality of life among patients with PIDs. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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