Multiscale segmentation of the skull in MR images for MRI-based attenuation correction of combined MR/PET.
Background and Objective: Combined magnetic resonance/positron emission tomography (MR/PET) is a relatively new, hybrid imaging modality. MR-based attenuation correction often requires segmentation of the bone on MR images. In this study, we present an automatic segmentation method for the skull on...
| Publicado en: | Journal of the American Medical Informatics Association Vol. 20; no. 6; pp. 1037 - 1046 |
|---|---|
| Autores principales: | , |
| Formato: | research Journal Article |
| Publicado: |
Oxford University Press / USA
Nov2013
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104103807&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104103807 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10675027 FZ9 jtl: Journal of the American Medical Informatics Association issn: 10675027 maglogo: N pubinfo: dt: Nov2013 vid: 20 iid: 6 pid: 622 pub: Oxford University Press / USA artinfo: ui: 104103807 NLM23761683 2012338851 10.1136/amiajnl-2012-001544 NLM23761683 PMC3822115 104103807 ppf: 1037 ppct: 9 formats: tig: atl: Multiscale segmentation of the skull in MR images for MRI-based attenuation correction of combined MR/PET. aug: au: Yang, Xiaofeng Fei, Baowei affil: Department of Radiology and Imaging Sciences, Center for Systems Imaging, Emory University, Atlanta, Georgia, USA. sug: subj: Brain Pathology Magnetic Resonance Imaging Methods Tomography, Emission-Computed Methods Skull Pathology Brain Radiography Diagnosis, Computer Assisted Human Mathematics Phantoms, Imaging Skull Radiography ab: Background and Objective: Combined magnetic resonance/positron emission tomography (MR/PET) is a relatively new, hybrid imaging modality. MR-based attenuation correction often requires segmentation of the bone on MR images. In this study, we present an automatic segmentation method for the skull on MR images for attenuation correction in brain MR/PET applications.Materials and Methods: Our method transforms T1-weighted MR images to the Radon domain and then detects the features of the skull image. In the Radon domain we use a bilateral filter to construct a multiscale image series. For the repeated convolution we increase the spatial smoothing in each scale and make the width of the spatial and range Gaussian function doubled in each scale. Two filters with different kernels along the vertical direction are applied along the scales from the coarse to fine levels. The results from a coarse scale give a mask for the next fine scale and supervise the segmentation in the next fine scale. The use of the multiscale bilateral filtering scheme is to improve the robustness of the method for noise MR images. After combining the two filtered sinograms, the reciprocal binary sinogram of the skull is obtained for the reconstruction of the skull image.Results: This method has been tested with brain phantom data, simulated brain data, and real MRI data. For real MRI data the Dice overlap ratios are 92.2%±1.9% between our segmentation and manual segmentation.Conclusions: The multiscale segmentation method is robust and accurate and can be used for MRI-based attenuation correction in combined MR/PET. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|