Clinical practice: Helicobacter pylori infection in childhood.
Helicobacter pylori infection is recognised as a cause of gastritis and peptic ulcer disease (PUD) and usually acquired during the first years of life. While there is a decline in the prevalence of H. pylori infection in northern and western European countries, the infection is still common in south...
| Publicado en: | European Journal of Pediatrics Vol. 172; no. 11; pp. 1427 - 1435 |
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| Formato: | review Journal Article |
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Springer Nature
Nov2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104103985&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104103985 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03406199 CR1 jtl: European Journal of Pediatrics issn: 03406199 maglogo: N pubinfo: dt: Nov2013 vid: 172 iid: 11 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104103985 NLM23015042 2012339228 10.1007/s00431-012-1823-4 NLM23015042 104103985 ppf: 1427 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Clinical practice: Helicobacter pylori infection in childhood. aug: au: Ertem, Deniz affil: Division of Pediatric Gastroenterology, Hepatology and Nutrition, Marmara University School of Medicine, Fevzi Çakmak Mah. Mimar Sinan Cad. No 41, Pendik, Istanbul, Turkey, dertem@hotmail.com. sug: subj: Helicobacter Infections Complications Helicobacter Infections Diagnosis Helicobacter Infections Drug Therapy Helicobacter Infections Epidemiology Helicobacter Pylori Antibiotics Therapeutic Use Child Drug Therapy, Combination Proton Pump Inhibitors Therapeutic Use Risk Factors World Health Child: 6-12 years ab: Helicobacter pylori infection is recognised as a cause of gastritis and peptic ulcer disease (PUD) and usually acquired during the first years of life. While there is a decline in the prevalence of H. pylori infection in northern and western European countries, the infection is still common in southern and eastern parts of Europe and Asia. Symptoms of H. pylori-related PUD are nonspecific in children and may include epigastric pain, nausea and/or vomiting, anorexia, iron deficiency anaemia and hematemesis. Besides, only a small proportion of children develop symptoms and clinically relevant gastrointestinal disease. H. pylori infection can be diagnosed either by invasive tests requiring endoscopy and biopsy or non-invasive tests including the (13)C-urea breath test, detection of H. pylori antigen in stool and detection of antibodies in serum, urine and saliva. The aim of treatment is at least 90 % eradication rate of the bacteria, and a combination of two antibiotics plus a proton pump inhibitor has been recommended as first-line treatment. However, frequent use of antibiotics during childhood is associated with a decline in eradication rates and the search for new treatment strategies as well. This is an overview of the latest knowledge and evidence-based guidelines regarding clinical presentation, diagnosis and treatment of H. pylori infection in childhood. pubtype: Academic Journal doctype: review Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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