Effects of infant cereals with different carbohydrate profiles on colonic function--randomised and double-blind clinical trial in infants aged between 6 and 12 months--pilot study.

Infant cereals are often the elected foodstuff for beginning complementary feeding and provide carbohydrates which are different to those found in maternal milk. The objective of this preliminary study was to ascertain the colonic effects of two infant cereals, with different carbohydrate profiles,...

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Publicado en:European Journal of Pediatrics Vol. 172; no. 11; pp. 1535 - 1543
Autores principales: Bernal, María José, Periago, María Jesús, Martínez, Rosario, Ortuño, Inmaculada, Sánchez-Solís, Manuel, Ros, Gaspar, Romero, Fernando, Abellán, Pedro
Formato: research randomized controlled trial Journal Article
Publicado: Springer Nature Nov2013
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2013
      vid: 172
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00431-013-2079-3
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        atl: Effects of infant cereals with different carbohydrate profiles on colonic function--randomised and double-blind clinical trial in infants aged between 6 and 12 months--pilot study.
      aug:
        au:
          Bernal, María José
          Periago, María Jesús
          Martínez, Rosario
          Ortuño, Inmaculada
          Sánchez-Solís, Manuel
          Ros, Gaspar
          Romero, Fernando
          Abellán, Pedro
        affil: Global Technology Center For Infant Nutrition, Hero Group, Avda. Murcia 1, 30820, Alcantarilla, Murcia, Spain, mjose.bernal@hero.es.
      sug:
        subj:
          Cereals
          Cereals Metabolism
          Colon Physiology
          Dietary Carbohydrates Metabolism
          Infant Nutritional Physiology Physiology
          Biological Markers Metabolism
          Colon Metabolism
          Colon Microbiology
          Double-Blind Studies
          Fatty Acids, Volatile Metabolism
          Feces
          Feces Microbiology
          Female
          Human
          Hydrogen-Ion Concentration
          Immunoglobulins Metabolism
          Infant
          Male
          Microbiologic Phenomena
          Pilot Studies
          Infant: 1-23 months
          Female
          Male
      ab: Infant cereals are often the elected foodstuff for beginning complementary feeding and provide carbohydrates which are different to those found in maternal milk. The objective of this preliminary study was to ascertain the colonic effects of two infant cereals, with different carbohydrate profiles, in a randomised and double-blind trial in healthy infants. Nineteen term infants between 6.3 and 9.8 months of age were enrolled, after written informed consent was obtained from parents. Ten subjects were allocated to take infant cereal A and nine, infant cereal B. An intervention period was 2 months, with five visits every 15 days, to take anthropometric measurements and faeces samples for the analysis of microbiota, short-chain fatty acids concentration (SCFA), pH value and secretory immunoglobulin A (sIgA). An adequate growth and stool frequency was registered in both intervention groups. Faecal counts of Bifidobacterium, Lactobacillus, Enterobacteriaceae, Enterococcus, Clostridium and Bacteroides did not show any statistical differences. However, a significantly (P < 0.05) higher butyric acid and sIgA, and lower faecal pH were observed in infants who had ingested infant cereal A, with a higher ratio complex/simple carbohydrates. In conclusion, small changes in the carbohydrate profile of infant cereals could lead to significant differences in parameters related to fermentative activity of intestinal microbiota.
      pubtype: Academic Journal
      doctype:
        research
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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