Cloud infrastructures for in silico drug discovery: economic and practical aspects.

Cloud computing opens new perspectives for small-medium biotechnology laboratories that need to perform bioinformatics analysis in a flexible and effective way. This seems particularly true for hybrid clouds that couple the scalability offered by generalpurpose public clouds with the greater control...

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Publicado en:BioMed Research International Vol. 2013; pp. 138012 - 138013
Autores principales: D'Agostino, Daniele, Clematis, Andrea, Quarati, Alfonso, Cesini, Daniele, Chiappori, Federica, Milanesi, Luciano, Merelli, Ivan
Formato: Journal Article
Publicado: Wiley-Blackwell 2013
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Cloud infrastructures for in silico drug discovery: economic and practical aspects.
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        au:
          D'Agostino, Daniele
          Clematis, Andrea
          Quarati, Alfonso
          Cesini, Daniele
          Chiappori, Federica
          Milanesi, Luciano
          Merelli, Ivan
        affil: Institute of Applied Mathematics and Information Technologies, National Research Council of Italy, via de Marini 6, 16149 Genoa, Italy.
      sug:
        subj:
          Computer Simulation
          Computing Methodologies
          Drug Discovery
          Biotechnology
      ab: Cloud computing opens new perspectives for small-medium biotechnology laboratories that need to perform bioinformatics analysis in a flexible and effective way. This seems particularly true for hybrid clouds that couple the scalability offered by generalpurpose public clouds with the greater control and ad hoc customizations supplied by the private ones. A hybrid cloud broker, acting as an intermediary between users and public providers, can support customers in the selection of the most suitable offers, optionally adding the provisioning of dedicated services with higher levels of quality. This paper analyses some economic and practical aspects of exploiting cloud computing in a real research scenario for the in silico drug discovery in terms of requirements, costs, and computational load based on the number of expected users. In particular, our work is aimed at supporting both the researchers and the cloud broker delivering an IaaS cloud infrastructure for biotechnology laboratories exposing different levels of nonfunctional requirements.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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