Estimation of the Lateral Ventricles Volumes from a 2D Image and Its Relationship with Cerebrospinal Fluid Flow.

Purpose. This work suggests a fast estimation method of the lateral ventricles volume from a 2D image and then determines if this volume is correlated with the cerebrospinal fluid flow at the aqueductal and cerebral levels in neurodegenerative diseases. Materials and Methods. FForty-five elderly pat...

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Published in:BioMed Research International Vol. 2013; pp. 215989 - 215990
Main Authors: Bader, Chaarani, Cyrille, Capel, Jadwiga, Zmudka, Joel, Daouk, Fichten, Anthony, Catherine, Gondry-Jouet, Roger, Bouzerar, Olivier, Balédent
Format: Journal Article
Published: Wiley-Blackwell 2013
Online Access:View this record in EBSCOhost
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      dt: 2013
      vid: 2013
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Estimation of the Lateral Ventricles Volumes from a 2D Image and Its Relationship with Cerebrospinal Fluid Flow.
      aug:
        au:
          Bader, Chaarani
          Cyrille, Capel
          Jadwiga, Zmudka
          Joel, Daouk
          Fichten, Anthony
          Catherine, Gondry-Jouet
          Roger, Bouzerar
          Olivier, Balédent
        affil: Department of Imaging, Jules Verne University of Picardy and Amiens University Hospital, 80054 Amiens Cedex, France.
      sug:
        subj:
          Alzheimer's Disease Cerebrospinal Fluid
          Dementia, Vascular Cerebrospinal Fluid
          Hydrocephalus, Normal Pressure Cerebrospinal Fluid
          Cerebral Ventricles Pathology
          Aged
          Alzheimer's Disease Pathology
          Alzheimer's Disease Radiography
          Brain Physiopathology
          Brain Radiography
          Dementia, Vascular Pathology
          Dementia, Vascular Radiography
          Female
          Hydrocephalus Cerebrospinal Fluid
          Hydrocephalus, Normal Pressure Pathology
          Hydrocephalus, Normal Pressure Radiography
          Magnetic Resonance Imaging
          Male
          Aged: 65+ years
          Female
          Male
      ab: Purpose. This work suggests a fast estimation method of the lateral ventricles volume from a 2D image and then determines if this volume is correlated with the cerebrospinal fluid flow at the aqueductal and cerebral levels in neurodegenerative diseases. Materials and Methods. FForty-five elderly patients suffering from Alzheimer's disease (19), normal pressure hydrocephalus (13), and vascular dementia (13) were involved and underwent anatomical and phase contrast MRI scans. Lateral ventricles and stroke volumes were assessed on anatomical and phase contrast scans, respectively. A common reference plane was used to calculate the lateral ventricles' area on 2D images. Results. The largest volumes were observed in hydrocephalus patients. The linear regression between volumes and areas was computed, and a strong positive correlation was detected (R² = 0.9). A derived equation was determined to represent the volumes for any given area. On the other hand, no significant correlations were detected between ventricles and stroke volumes (R² ≤ 0.15). Conclusion. Lateral ventricles volumes are significantly proportional to the 2D reference section area and could be used for patients' follow-up even if 3D images are unavailable. The cerebrospinal fluid fluctuations in brain disorders may depend on many physiological parameters other than the ventricular morphology.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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