CT imaging features of acinar cell carcinoma and its hepatic metastases.

Objective: To evaluate and describe the computed tomography features of pure acinar cell carcinoma (ACC) and its liver metastases.Methods: Thirty patients were evaluated. Two radiologists evaluated imaging findings for each tumor for size, location, internal density, enhancement, tumor calcification...

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Publicado en:Abdominal Imaging Vol. 38; no. 6; pp. 1383 - 1391
Autores principales: Bhosale, P, Balachandran, A, Wang, H, Wei, W, Hwang, R F, Fleming, J B, Varadhachary, G, Charnsangavej, C, Tamm, E
Formato: research Journal Article
Publicado: Springer Nature Dec2013
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2013
      vid: 38
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      pub: Springer Nature
      place: New York, New York
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        atl: CT imaging features of acinar cell carcinoma and its hepatic metastases.
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          Bhosale, P
          Balachandran, A
          Wang, H
          Wei, W
          Hwang, R F
          Fleming, J B
          Varadhachary, G
          Charnsangavej, C
          Tamm, E
        affil: Department of Diagnostic Radiology, UT MD Anderson Cancer Center, 1400 Pressler Street, Unit 1473, Houston, TX, 77030, USA, priya.bhosale@mdanderson.org.
      sug:
        subj:
          Adenocarcinoma Radiography
          Liver Neoplasms Radiography
          Pancreatic Neoplasms Radiography
          Tomography, X-Ray Computed Methods
          Adult
          Aged
          Aged, 80 and Over
          Adenocarcinoma
          Contrast Media Diagnostic Use
          Female
          Human
          Liver Neoplasms
          Neoplasm Metastasis
          Male
          Middle Age
          Pancreatic Neoplasms Pathology
          Growth Substances Diagnostic Use
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
          Male
      ab: Objective: To evaluate and describe the computed tomography features of pure acinar cell carcinoma (ACC) and its liver metastases.Methods: Thirty patients were evaluated. Two radiologists evaluated imaging findings for each tumor for size, location, internal density, enhancement, tumor calcifications, pancreatic, and common biliary ductal obstructions and metastases.Results: 70 % were male. Fourteen tumors were located in the pancreatic head, 14 in the tail, one in the neck, and one in the uncinate process. Abdominal pain was the most common presenting symptom (93 %), 20 % had pancreatitis and 17 % had obstructive jaundice. The average tumor size was 7 cm, 97 % of tumors were solid, well circumscribed (73 %); isodense to normal pancreatic parenchyma (40 %) on the non-contrast study, hypodense on the arterial (47 %), and hypodense on the portal venous (37 %) phase. 30 % patients had pancreatic ductal dilation, 10 % had pancreatic ductal ingrowth, 6 % had calcifications, and 20 % had central necrosis, and 31 % (5/16) showed biliary ductal dilation. At presentation, 50 % had metastatic adenopathy and 40 % patients had liver metastases, which typically were well circumscribed, hypoattenuating to the hepatic parenchyma on all the phases of contrast enhancement and had a lobulated margin.Conclusion: ACCs of the pancreas often present as large, well circumscribed, solid masses commonly in males. Despite their large size, they may not cause CBD obstruction.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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