Ultra-fast speech comprehension in blind subjects engages primary visual cortex, fusiform gyrus, and pulvinar - a functional magnetic resonance imaging (fMRI) study.

Background: Individuals suffering from vision loss of a peripheral origin may learn to understand spoken language at a rate of up to about 22 syllables (syl) per second - exceeding by far the maximum performance level of normal-sighted listeners (ca. 8 syl/s). To further elucidate the brain mechanis...

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Publicado en:BMC Neuroscience Vol. 14; no. 1; pp. 74 - 75
Autores principales: Dietrich, Susanne, Hertrich, Ingo, Ackermann, Hermann
Formato: research Journal Article
Publicado: BioMed Central 2013
Acceso en línea:Ver este registro en EBSCOhost
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      pub: BioMed Central
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        10.1186/1471-2202-14-74
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        atl: Ultra-fast speech comprehension in blind subjects engages primary visual cortex, fusiform gyrus, and pulvinar - a functional magnetic resonance imaging (fMRI) study.
      aug:
        au:
          Dietrich, Susanne
          Hertrich, Ingo
          Ackermann, Hermann
        affil: Center for Neurology/Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Hoppe-Seyler-Str, 3, D-72076, Tübingen, Germany. susanne.dietrich@med.uni-tuebingen.de.
      sug:
        subj:
          Blindness
          Brain Mapping
          Cerebral Cortex Physiology
          Readability
          Speech Perception
          Adult
          Female
          Image Interpretation, Computer Assisted
          Magnetic Resonance Imaging
          Male
          Thalamus Physiology
          Time Factors
          Occipital Lobe Physiology
          Persons with Disabilities
          Adult: 19-44 years
          Female
          Male
      ab: Background: Individuals suffering from vision loss of a peripheral origin may learn to understand spoken language at a rate of up to about 22 syllables (syl) per second - exceeding by far the maximum performance level of normal-sighted listeners (ca. 8 syl/s). To further elucidate the brain mechanisms underlying this extraordinary skill, functional magnetic resonance imaging (fMRI) was performed in blind subjects of varying ultra-fast speech comprehension capabilities and sighted individuals while listening to sentence utterances of a moderately fast (8 syl/s) or ultra-fast (16 syl/s) syllabic rate.Results: Besides left inferior frontal gyrus (IFG), bilateral posterior superior temporal sulcus (pSTS) and left supplementary motor area (SMA), blind people highly proficient in ultra-fast speech perception showed significant hemodynamic activation of right-hemispheric primary visual cortex (V1), contralateral fusiform gyrus (FG), and bilateral pulvinar (Pv).Conclusions: Presumably, FG supports the left-hemispheric perisylvian "language network", i.e., IFG and superior temporal lobe, during the (segmental) sequencing of verbal utterances whereas the collaboration of bilateral pulvinar, right auditory cortex, and ipsilateral V1 implements a signal-driven timing mechanism related to syllabic (suprasegmental) modulation of the speech signal. These data structures, conveyed via left SMA to the perisylvian "language zones", might facilitate - under time-critical conditions - the consolidation of linguistic information at the level of verbal working memory.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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