Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis.

Protection against deadly pathogens requires the production of high-affinity antibodies by B cells, which are generated in germinal centers (GCs). Alteration of the GC developmental program is common in many B cell malignancies. Identification of regulators of the GC response is crucial to develop t...

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Publicado en:	Journal of Clinical Investigation Vol. 123; no. 12; pp. 5009 - 5023
Autores principales:	Caganova, Marieta, Carrisi, Chiara, Varano, Gabriele, Mainoldi, Federica, Zanardi, Federica, Germain, Pierre-Luc, George, Laura, Alberghini, Federica, Ferrarini, Luca, Talukder, Asoke K, Ponzoni, Maurilio, Testa, Giuseppe, Nojima, Takuya, Doglioni, Claudio, Kitamura, Daisuke, Toellner, Kai-M, Su, I-Hsin, Casola, Stefano
Formato:	research Journal Article
Publicado:	American Society for Clinical Investigation Dec2013
Acceso en línea:	Ver este registro en EBSCOhost