Cerebral activation evoked by the mirror illusion of the hand in stroke patients compared to normal subjects.
BACKGROUND: Mirror therapy (MT) was found to improve motor function after stroke, but its neural mechanisms remain unclear, especially in single stroke patients. OBJECTIVES: The following imaging study was designed to compare brain activation patterns evoked by the mirror illusion in single stroke p...
| Publicado en: | NeuroRehabilitation Vol. 33; no. 4; pp. 593 - 604 |
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| Autores principales: | , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Sage Publications Inc.
2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104125284&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104125284 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10538135 3RE jtl: NeuroRehabilitation issn: 10538135 maglogo: N pubinfo: dt: 2013 vid: 33 iid: 4 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 104125284 92940708 10.3233/NRE-130999 NLM24018372 104125284 ppf: 593 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Cerebral activation evoked by the mirror illusion of the hand in stroke patients compared to normal subjects. aug: au: Wang, Jing Fritzsch, Claire Bernarding, Johannes Krause, Thomas Mauritz, Karl-Heinz Brunetti, Maddalena Dohle, Christian affil: Medical Faculty, Institute for Biometry and Medical Computer Science, University Magdeburg, Magdeburg, Germany sug: subj: Stroke Rehabilitation Rehabilitation Methods Optics Brain Physiology Human Funding Source Case Control Studies Hemiplegia Videorecording Magnetic Resonance Imaging Methods Male Female Adult Middle Age Descriptive Statistics Data Analysis Software Goodness of Fit Chi Square Test Wilcoxon Signed Rank Test Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: BACKGROUND: Mirror therapy (MT) was found to improve motor function after stroke, but its neural mechanisms remain unclear, especially in single stroke patients. OBJECTIVES: The following imaging study was designed to compare brain activation patterns evoked by the mirror illusion in single stroke patients with normal subjects. METHODS: Fifteen normal volunteers and five stroke patients with severe arm paresis were recruited. Cerebral activations during movement mirroring by means of a video chain were recorded with functional magnetic resonance imaging (fMRI). Single-subject analysis was performed using SPM 8. RESULTS: For normal subjects, ten and thirteen subjects displayed lateralized cerebral activations evoked by the mirror illusion while moving their right and left hand respectively. The magnitude of this effect in the precuneus contralateral to the seen hand was not dependent on movement speed or subjective experience. Negative correlation of activation strength with age was found for the right hand only. The activation pattern in stroke patients is comparable to that of normal subjects and present in four out of five patients. CONCLUSIONS: In summary, the mirror illusion can elicit cerebral activation contralateral to the perceived hand in the majority of single normal subjects, but not in all of them. This is similar even in stroke patients with severe hemiparesis. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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