Prevalence of Helicobacter pylori in adenotonsillar hypertrophy in children.
Conclusion: Our results encourage the notion that the pharynx could be an extragastric reservoir of Helicobacter pylori (HP). The study confirmed the presence of HP in adenotonsillar tissue in children. It could have importance in the pathophysiology of upper respiratory diseases. However, its preci...
| Publicado en: | Acta Oto-Laryngologica Vol. 134; no. 1; pp. 88 - 93 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Jan2014
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104126045&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104126045 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00016489 B6D jtl: Acta Oto-Laryngologica issn: 00016489 maglogo: Y pubinfo: dt: Jan2014 vid: 134 iid: 1 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 104126045 93277933 10.3109/00016489.2013.840924 NLM24256044 104126045 ppf: 88 ppct: 5 formats: fmt: @attributes: type: P tig: atl: Prevalence of Helicobacter pylori in adenotonsillar hypertrophy in children. aug: au: Kraus, Jaroslav Nártov, Eva Pavlík, Emil Katra, Rami Šterzl, Ivan Astl, Jaromír affil: Department of Otorhinolaryngology, Hospital of Rudolf & Stefanie Benešov sug: subj: Helicobacter Pylori Immunology Tonsil Physiopathology Adenoids Physiopathology Hypertrophy Physiopathology Human Prospective Studies Child, Preschool Child Tonsillectomy Adenoidectomy Polymerase Chain Reaction Genotype Funding Source Female Male Child, Preschool: 2-5 years Child: 6-12 years Female Male ab: Conclusion: Our results encourage the notion that the pharynx could be an extragastric reservoir of Helicobacter pylori (HP). The study confirmed the presence of HP in adenotonsillar tissue in children. It could have importance in the pathophysiology of upper respiratory diseases. However, its precise role in these processes remains unclear and requires further studies. Objective: A prospective study was carried out to evaluate the presence of HP in tonsillar and adenoid tissue in children. The study focused on real-time PCR analyzing CagA and VacA genotypes of HP strains. Methods: A total of 37 consecutive pediatric patients with adenotonsillar hypertrophy indicated for surgery were observed in a prospective study. Adenoidectomy and/or tonsillectomy was performed in each patient; 49 specimens were taken, 32 from adenoids and 17 from tonsils. The presence of HP and its genotype were tested in all samples by real-time PCR analysis. Results: Of 49 samples analyzed, 48 were positive for the presence of HP (98%), so only 1 sample was negative. While the genotype VacAs1bm2 was definitely dominant in adenoid tissue, wider distribution was observed in tonsillar tissue. Cag+ strains represented one-fifth of all samples (21%). pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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