Left Atrial Volume Index in Healthy Subjects: Clinical and Echocardiographic Correlates.
Left atrial ( LA) size is related to cardiovascular morbidity and mortality. The relative role of multiple determinants of LA morphology in healthy subjects remains incompletely defined. The aim of this study is to define normal ranges for LA diameters and volume index ( LAVi), and to investigate cl...
| Publicado en: | Echocardiography Vol. 30; no. 9; pp. 1001 - 1008 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | diagnostic images research tables/charts tracings Journal Article |
| Publicado: |
Wiley-Blackwell
Oct2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104140702&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104140702 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 07422822 GSE jtl: Echocardiography issn: 07422822 maglogo: Y pubinfo: dt: Oct2013 vid: 30 iid: 9 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104140702 90634419 10.1111/echo.12217 NLM23594028 104140702 ppf: 1001 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Left Atrial Volume Index in Healthy Subjects: Clinical and Echocardiographic Correlates. aug: au: D'Andrea, Antonello Riegler, Lucia Rucco, Maria Antonietta Cocchia, Rosangela Scarafile, Raffaella Salerno, Gemma Martone, Francesca Vriz, Olga Caso, Pio Calabrò, Raffaele Bossone, Eduardo Russo, Maria Giovanna affil: Chair of Cardiology, Second University of Naples sug: subj: Echocardiography Cardiovascular Risk Factors Heart Atrium, Left Physiology Human Descriptive Statistics Middle Age Male Female Adult Aged Aged, 80 and Over Italy Analysis of Variance Post Hoc Analysis Correlation Coefficient Data Analysis Software Interrater Reliability Intrarater Reliability Multiple Linear Regression Middle Aged: 45-64 years Adult: 19-44 years Aged: 65+ years Aged, 80 & over Male Female ab: Left atrial ( LA) size is related to cardiovascular morbidity and mortality. The relative role of multiple determinants of LA morphology in healthy subjects remains incompletely defined. The aim of this study is to define normal ranges for LA diameters and volume index ( LAVi), and to investigate clinical and echocardiographic correlates. A total of 1480 healthy individuals (mean age 36.1 ± 15.5 years, range 20-80; 61% males) underwent a comprehensive transthoracic echocardiography exam including assessment of LAVi calculated using the biplane area-length method at the apical four-chamber and two-chamber views at ventricular end systole (maximum LA size) and indexed for body surface area ( BSA). Mean LAVi in the overall population was 29.5 ± 10.8 mL/m2 (range: 26.1-41.8 mL/m2). Distinct higher values were found in subjects ≥50 years as compared with those <50 years of age (33.4 ± 12.5 vs. 29.1 ± 13.5; P < 0.001). On univariate analysis, LA volume was significantly associated with age (r = 0.48, P < 0.0001), male gender (r = 0.28, P < 0.05), BSA (r = 0.51, P < 0.0001), mitral E/E' (r = 0.47, P < 0.0001), LV end-diastolic volume (r = 0.52, P < 0.0001), and LV mass index (r = 0.31, P < 0.05). Multivariable analysis identified age, BSA, LV end-diastolic volume, and mitral E/E' ratio as the only independent determinants of LA volume (model R2 = 0.54, P < 0.0001). Gender was an independent predictor of most absolute LA volume, but following normalization to BSA, some associations became nonsignificant. In healthy individuals LAVi vary significantly by age, BSA, diastolic function, and LV dimensions, with lesser effects of gender. pubtype: Academic Journal doctype: diagnostic images research tables/charts tracings Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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