A Comparison of Leak Compensation in Acute Care Ventilators During Noninvasive and Invasive Ventilation: A Lung Model Study.

BACKGROUND: Although leak compensation has been widely introduced to acute care ventilators to improve patient-ventilator synchronization in the presence of system leaks, there are no data on these ventilators' ability to prevent triggering and cycling asynchrony. The goal of this study was to evalu...

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Published in:Respiratory Care Vol. 58; no. 12; pp. 2027 - 2038
Main Authors: Jun Oto, Chenelle, Christopher T., Marchese, Andrew D., Kacmarek, Robert M.
Format: research tables/charts Journal Article
Published: Mary Ann Liebert, Inc. Dec2013
Online Access:View this record in EBSCOhost
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      dt: Dec2013
      vid: 58
      iid: 12
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      pub: Mary Ann Liebert, Inc.
      place: New Rochelle, New York
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        atl: A Comparison of Leak Compensation in Acute Care Ventilators During Noninvasive and Invasive Ventilation: A Lung Model Study.
      aug:
        au:
          Jun Oto
          Chenelle, Christopher T.
          Marchese, Andrew D.
          Kacmarek, Robert M.
        affil: Respiratory Care Services, Massachusetts General Hospital, Boston, Massachusetts
      sug:
        subj:
          Respiration, Artificial Equipment and Supplies
          Ventilators, Mechanical Evaluation
          Acute Care
          Respiratory Mechanics
          Noninvasive Procedures
          Invasive Procedures
          Models, Anatomic
          Simulations
          Positive End-Expiratory Pressure
          Comparative Studies
          Funding Source
          Descriptive Statistics
          Tidal Volume
          Data Analysis Software
          Education, Continuing (Credit)
      ab: BACKGROUND: Although leak compensation has been widely introduced to acute care ventilators to improve patient-ventilator synchronization in the presence of system leaks, there are no data on these ventilators' ability to prevent triggering and cycling asynchrony. The goal of this study was to evaluate the ability of leak compensation in acute care ventilators during invasive and noninvasive ventilation (NIV). METHODS: Using a lung simulator, the impact of system leaks was compared on 7 ICU ventilators and 1 dedicated NIV ventilator during triggering and cycling at 2 respiratory mechanics (COPD and ARDS models) settings, various modes of ventilation (NIV mode [pressure support ventilation], and invasive mode [pressure support and continuous mandatory ventilation]), and 2 PEEP levels (5 and 10 cm H2O). Leak levels used were up to 35-36 L/min in NIV mode and 26-27 L/min in invasive mode. RESULTS: Although all of the ventilators were able to synchronize with the simulator at baseline, only 4 of the 8 ventilators synchronized to all leaks in NIV mode, and 2 of the 8 ventilators in invasive mode. The number of breaths to synchronization was higher during increasing than during decreasing leak. In the COPD model, miss-triggering occurred more frequently and required a longer time to stabilize tidal volume than in the ARDS model. The PB840 required fewer breaths to synchronize in both invasive and noninvasive modes, compared with the other ventilators (P < .001). CONCLUSIONS: Leak compensation in invasive and noninvasive modes has wide variations between ventilators. The PB840 and the V60 were the only ventilators to acclimate to all leaks, but there were differences in performance between these 2 ventilators. It is not clear if these differences have clinical importance.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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