No superior performance of hydroxyapatite-coated acetabular cups over porous-coated cups.

Background and purpose Hydroxyapatite (HA) coating is believed to improve bone-implant ingrowth and long-term survival of prostheses. Recent studies, however, have challenged this view. Furthermore, HA particles may produce third-body wear and initiate aseptic loosening of implants. We report the pe...

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Publicado en:Acta Orthopaedica Vol. 84; no. 6; pp. 544 - 549
Autores principales: Valancius, Kestutis, Søballe, Kjeld, Nielsen, Poul T, Laursen, Mogens B
Formato: pictorial research tables/charts randomized controlled trial Journal Article
Publicado: Medical Journals Sweden AB Dec2013
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2013
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      pub: Medical Journals Sweden AB
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        atl: No superior performance of hydroxyapatite-coated acetabular cups over porous-coated cups.
      aug:
        au:
          Valancius, Kestutis
          Søballe, Kjeld
          Nielsen, Poul T
          Laursen, Mogens B
        affil: Farsoe Clinic of Hip and Knee Arthroplasty, Department of Orthopaedic Surgery, Aalborg University Hospital, Aalborg
      sug:
        subj:
          Arthroplasty, Replacement, Hip Equipment and Supplies
          Prostheses and Implants
          Biocompatible Materials
          Quality Assessment
          Treatment Outcomes
          Human
          Prospective Studies
          Randomized Controlled Trials
          Absorptiometry, Photon
          Clinical Assessment Tools
          Female
          Male
          Null Hypothesis
          Analysis of Variance
          Descriptive Statistics
          Kaplan-Meier Estimator
          Survival Analysis
          Middle Age
          Adult
          Aged
          Aged, 80 and Over
          Repeated Measures
          Middle Aged: 45-64 years
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Female
          Male
      ab: Background and purpose Hydroxyapatite (HA) coating is believed to improve bone-implant ingrowth and long-term survival of prostheses. Recent studies, however, have challenged this view. Furthermore, HA particles may produce third-body wear and initiate aseptic loosening of implants. We report the performance of HA- and porous-coated acetabular cups in a prospective randomized trial. Methods This was an 8-year follow-up study of our previously published prospective randomized study to compare clinical outcomes, survival, periprosthetic bone mineral density, migration, and wear rates of HA- and porous-coated acetabular cups. Dual X-ray absorptiometry (DXA) and Ein Bild Roentgen Analyse (EBRA) measurements were used. 100 patients who underwent unilateral cementless total hip arthroplasty were randomized to either porous-coated cups or HA-coated cups. Patients were examined preoperatively and at 3, 6, and 9 months, and also 1, 3, and 8 years after surgery. 81 patients were available for 8-year follow-up, 40 with porous-coated cups and 41 with HA-coated cups. Results Age, sex, bone mineral density, and clinical results (Harris hip score) were similar in the 2 groups. The survival, wear, and migration patterns of the cups were also similar in both groups. The results of periprosthetic bone mineral density scans in region of interest 2 was in favor of the porous-coated cups, but there were no differences between the 2 groups in all the remaining regions of interest. Interpretation HA coating had no statistically significant effect on clinical results, survival, wear, or migration at the 8-year follow-up.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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