A Short-Term Evaluation of the Relationship Between Plasma Ascorbic Acid Levels and Periodontal Disease in Systemically Healthy and Type 2 Diabetes Mellitus Subjects.
Background: Deficient ascorbic acid levels (AALs) and Type 2 diabetes mellitus (T2DM) are associated with periodontal disease. This study evaluated the relationship between plasma AAL and periodontitis in systemically healthy and T2DM subjects, which to the best of our knowledge is being reported fo...
| Publicado en: | Journal of Dietary Supplements Vol. 10; no. 2; pp. 93 - 105 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Jun2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104175120&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104175120 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 19390211 2Y62 jtl: Journal of Dietary Supplements issn: 19390211 maglogo: N pubinfo: dt: Jun2013 vid: 10 iid: 2 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 104175120 87915462 10.3109/19390211.2013.790332 NLM23725523 104175120 ppf: 93 ppct: 12 formats: fmt: @attributes: type: P tig: atl: A Short-Term Evaluation of the Relationship Between Plasma Ascorbic Acid Levels and Periodontal Disease in Systemically Healthy and Type 2 Diabetes Mellitus Subjects. aug: au: Gokhale, Neeraja H. Acharya, Anirudh B. Patil, Vidya S. Trivedi, Dheeraj J. Thakur, Srinath L. affil: Department of Periodontics, Sri Dharmasthala Manjunatheshwara College of Dental Sciences & Hospital, Sattur, Dharwad, Karnataka, India sug: subj: Ascorbic Acid Deficiency Risk Factors Periodontal Diseases Prevention and Control Diabetes Mellitus, Type 2 Complications Dietary Supplements Therapeutic Use Human Ascorbic Acid Blood Spectrophotometry Descriptive Statistics Data Analysis Software Post Hoc Analysis Paired T-Tests Male Female Adult Middle Age Pilot Studies Control Group Matched-Pair Analysis Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Background: Deficient ascorbic acid levels (AALs) and Type 2 diabetes mellitus (T2DM) are associated with periodontal disease. This study evaluated the relationship between plasma AAL and periodontitis in systemically healthy and T2DM subjects, which to the best of our knowledge is being reported for the first time. Methods: One hundred twenty subjects were categorized into four groups of 30 each as group 1: without periodontal disease; group 2: chronic gingivitis; group 3: chronic periodontitis, and group 4: chronic periodontitis and freshly diagnosed T2DM. Plaque index (PlI), sulcus bleeding index (SBI), and probing pocket depths (PPDs) were evaluated. Venous blood was evaluated for plasma AAL spectrophotometrically. Randomized subjects were subgrouped within groups 2-4, to receive either scaling and root planing (SRP) with dietary supplementation (450 mg) of ascorbic acid (AA) for two weeks or only SRP. After two weeks, the clinical parameters were reassessed. Tukey's multiple post hoc procedures and paired t test were used with the level of statistical significance adjusted to p ≤ .05. Results: AAL plasma levels were significantly greater in group 1 than in group 2 ( p = .0007) and in group 4 ( p = .0003). A significant reduction in the SBI was seen in the subgroups that received dietary supplementation of vitamin C within group 2 ( p = .0012) and group 4 ( p = .036). Conclusions: Plasma AAL is below the normal range in systemically healthy subjects with gingivitis and diabetics with periodontitis. Dietary AA supplementation with SRP improves the SBI in subjects with gingivitis and diabetics with periodontitis. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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