Nodular secondary syphilis in a woman.
We report the case of a 21-year-old woman with symmetrically distributed, ulcerated nodules and plaques on the face, neck and arms. Initial differential diagnoses included pyoderma or sarcoidosis based on the clinical presentation and histopathology with non-caseating granulomas. After inefficient t...
| Publicado en: | BMJ Case Reports pp. 1 - 5 |
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| Formato: | case study pictorial tables/charts Journal Article |
| Publicado: |
BMJ Publishing Group
May2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104176166&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104176166 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 1757790X B755 jtl: BMJ Case Reports issn: 1757790X maglogo: N pubinfo: dt: May2013 pid: 8280 pub: BMJ Publishing Group artinfo: ui: 104176166 88013081 10.1136/bcr-2013-009130 104176166 ppf: 1 ppct: 4 formats: tig: atl: Nodular secondary syphilis in a woman. aug: sug: subj: Syphilis Diagnosis Syphilis Pathology Skin Diseases, Infectious Diagnosis Skin Diseases, Infectious Pathology Female Young Adult Diagnosis, Differential Immunohistochemistry Penicillins Therapeutic Use Syphilis Drug Therapy Skin Diseases, Infectious Drug Therapy Female ab: We report the case of a 21-year-old woman with symmetrically distributed, ulcerated nodules and plaques on the face, neck and arms. Initial differential diagnoses included pyoderma or sarcoidosis based on the clinical presentation and histopathology with non-caseating granulomas. After inefficient treatment with topical and systemic fusidic acid and steroids, we diagnosed nodular secondary syphilis owing to positive serology and immunohistochemical staining of Treponema pallidum in lesional skin. After treatment with benzathine penicillin, skin lesions improved and antibody titres declined significantly within 3 months. Nodular skin lesions in secondary syphilis are rare with 15 reported cases within the last 20 years. Furthermore, the granulomatous histology is often misleading. Our patient's case suggests that the physicians should be aware of syphilis as a possible differential diagnosis also in patients outside a high-risk population for sexually transmitted diseases and with an unusual clinical presentation. pubtype: Academic Journal doctype: case study pictorial tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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