Pharmacodynamics of liposomal amphotericin B and flucytosine for cryptococcal meningoencephalitis: safe and effective regimens for immunocompromised patients.

Background: Cryptococcal meningoencephalitis is a lethal infection with relatively few therapeutic options. The optimal dosage of liposomal amphotericin B (LAmB) alone or in combination with flucytosine is not known.Methods: A murine model of cryptococcal meningoencephalitis was used. The fungal den...

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Bibliographic Details

Published in:	Journal of Infectious Diseases Vol. 208; no. 2; pp. 351 - 362
Main Authors:	O'Connor, Lucy, Livermore, Joanne, Sharp, Andrew D, Goodwin, Joanne, Gregson, Lea, Howard, Susan J, Felton, Timothy W, Schwartz, Julie A, Neely, Michael N, Harrison, Thomas S, Perfect, John R, Hope, William W
Format:	research Journal Article
Published:	Oxford University Press / USA Jul2013
Online Access:	View this record in EBSCOhost