A Comparison of Computer-Aided Detection (CAD) Effectiveness in Pulmonary Nodule Identification Using Different Methods of Bone Suppression in Chest Radiographs.

This study aimed to compare the diagnostic effectiveness of computer-aided detection (CAD) software (OnGuard™ 5.2) in combination with hardware-based bone suppression (dual-energy subtraction radiography (DESR)), software-based bone suppression (SoftView™, version 2.4), and standard posteroanterior...

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Publicado en:Journal of Digital Imaging Vol. 26; no. 4; pp. 651 - 657
Autores principales: Novak, Ronald, Novak, Nicholas, Gilkeson, Robert, Mansoori, Bahar, Aandal, Gunhild
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Aug2013
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: A Comparison of Computer-Aided Detection (CAD) Effectiveness in Pulmonary Nodule Identification Using Different Methods of Bone Suppression in Chest Radiographs.
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        au:
          Novak, Ronald
          Novak, Nicholas
          Gilkeson, Robert
          Mansoori, Bahar
          Aandal, Gunhild
        affil: Case Western Reserve University, 10900 Euclid Avenue Cleveland 44106 USA
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        subj:
          Diagnosis, Computer Assisted Methods
          Subtraction Technique
          Radiography, Thoracic
          Lung Neoplasms Diagnosis
          Lung Radiography
          Software
          Bone and Bones Radiography
          False Positive Results
          Radiographic Image Enhancement
          Comparative Studies
          Retrospective Design
          Pilot Studies
          Chi Square Test
          kappa Statistic
          Summated Rating Scaling
          Sensitivity and Specificity
          McNemar's Test
          P-Value
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          Aged
          Aged, 80 and Over
          Female
          Male
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          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
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      ab: This study aimed to compare the diagnostic effectiveness of computer-aided detection (CAD) software (OnGuard™ 5.2) in combination with hardware-based bone suppression (dual-energy subtraction radiography (DESR)), software-based bone suppression (SoftView™, version 2.4), and standard posteroanterior images with no bone suppression. A retrospective pilot study compared the diagnostic performance of two commercially available methods of bone suppression when used with commercially available CAD software. Chest images from 27 patients with computed tomography (CT) and pathology-proven malignant pulmonary nodules (8-34 mm) and 25 CT-negative patient controls were used for analysis. The Friedman, McNemar, and chi-square tests were used to compare diagnostic performance and the kappa statistic was used to evaluate method agreement. The average number of regions of interest and false-positives per image identified by CAD were not found to be significantly different regardless of the bone suppression methods evaluated. Similarly, the sensitivity, specificity, and test efficiency were not found to be significantly different. Agreement between the methods was between poor and excellent. The accuracy of CAD (OnGuard™, version 5.2) is not statistically different with either DESR or SoftView™ (version 2.4) bone suppression technology in digital chest images for pulmonary nodule identification. Low values for sensitivity (<80 %) and specificity (<50 %) may limit their utility for clinical radiology.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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