Pharmacokinetic parameter sets of alfentanil revisited: optimal parameters for use in target controlled infusion and anaesthesia display systems.

Background: In open TCI and anaesthesia display systems, the choice of pharmacokinetic (PK) parameter sets of opioids is clinically relevant. Accuracy and bias of the PK models may be affected by administration mode and the co-administered hypnotic drug. We retrospectively evaluated the performance...

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Bibliographic Details
Published in:BJA: The British Journal of Anaesthesia Vol. 111; no. 2; pp. 197 - 209
Main Authors: Sigmond, N, Baechtold, M, Schumacher, P M, Hartwich, V, Schnider, T W, Luginbühl, M
Format: research Journal Article
Published: Elsevier B.V. Aug2013
Online Access:View this record in EBSCOhost