Decomposing Phenotype Descriptions for the Human Skeletal Phenome.

Over the course of the last few years there has been a significant amount of research performed on ontology-based formalization of phenotype descriptions. The intrinsic value and knowledge captured within such descriptions can only be expressed by taking advantage of their inner structure that impli...

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Publicado en:Biomedical Informatics Insights Vol. 6; pp. 1 - 15
Autores principales: Groza, Tudor, Hunter, Jane, Zankl, Andreas
Formato: research tables/charts Journal Article
Publicado: Sage Publications Inc. 2013
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Sage Publications Inc.
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        atl: Decomposing Phenotype Descriptions for the Human Skeletal Phenome.
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          Groza, Tudor
          Hunter, Jane
          Zankl, Andreas
        affil: School of ITee, University of Queensland, Australia
      sug:
        subj:
          Bone and Bones
          Resource Databases, Health
          Phenotype
          Classification
          Automation
          Bioinformatics
          Validation Studies
          Comparative Studies
          Descriptive Statistics
          Human
          Funding Source
      ab: Over the course of the last few years there has been a significant amount of research performed on ontology-based formalization of phenotype descriptions. The intrinsic value and knowledge captured within such descriptions can only be expressed by taking advantage of their inner structure that implicitly combines qualities and anatomical entities. We present a meta-model (the Phenotype Fragment Ontology) and a processing pipeline that enable together the automatic decomposition and conceptualization of phenotype descriptions for the human skeletal phenome. We use this approach to showcase the usefulness of the generic concept of phenotype decomposition by performing an experimental study on all skeletal phenotype concepts defined in the Human Phenotype Ontology.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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