Is the nystagmus pattern in hemi-labyrinthectomized subjects during positional alcohol nystagmus 2 similar to that found in patients with cupulolithiasis in the lateral semicircular canal?

Conclusion: A positional nystagmus pattern compatible with a condition of a heavy cupula (cupulolithiasis) in the lateral semicircular canal could be reproduced in hemi-labyrinthectomized subjects during positional alcohol nystagmus 2 (PAN 2). The nystagmus pattern was opposite to that found in the...

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Publicado en:Acta Oto-Laryngologica Vol. 133; no. 8; pp. 796 - 804
Autores principales: Tomanovic, Tatjana, Bergenius, Johan
Formato: pictorial research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Aug2013
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2013
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      pub: Taylor & Francis Ltd
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        atl: Is the nystagmus pattern in hemi-labyrinthectomized subjects during positional alcohol nystagmus 2 similar to that found in patients with cupulolithiasis in the lateral semicircular canal?
      aug:
        au:
          Tomanovic, Tatjana
          Bergenius, Johan
        affil: Department of Audiology and Neurotology, Diagnostics and Dizziness Unit, Karolinska University Hospital; Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institute, Stockholm, Sweden
      sug:
        subj:
          Nystagmus, Pathologic Physiopathology
          Posture Physiology
          Semicircular Canals Physiopathology
          Calculi Physiopathology
          Vestibule, Labyrinth Surgery
          Human
          Male
          Female
          Adult
          Middle Age
          Ethanol Pharmacodynamics
          Body Positions
          Analysis of Variance
          Descriptive Statistics
          Repeated Measures
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Conclusion: A positional nystagmus pattern compatible with a condition of a heavy cupula (cupulolithiasis) in the lateral semicircular canal could be reproduced in hemi-labyrinthectomized subjects during positional alcohol nystagmus 2 (PAN 2). The nystagmus pattern was opposite to that found in the same subjects during PAN 1. The affected side could not be judged by applying Ewald's second law. Objectives: To mimic the condition of a heavy cupula in the lateral semicircular canal by using unilaterally deafferented subjects during PAN 2 and compare (a) results reported in the literature with those of patients with cupulolithiasis, and (b) the nystagmus findings in the same subjects during PAN 1. Methods: Five hemi-labyrinthectomized subjects were studied during PAN 2 when they kept their heads pointed straight forward or turned sideways in the prone and supine positions, respectively. Results: When the subjects were examined with their heads turned in the supine or prone positions, the alcohol-induced nystagmus pattern was compatible with that of cupulolithiasis. When the head was pointed straight forward in the prone and supine positions, the nystagmus directions were opposite to those found during PAN 1. Directional preponderance was not seen for the apogeotropic nystagmus for either ampullofugal or ampullopetal deviation of the cupula.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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