Use of data from registered clinical trials to identify gaps in health research and development.
Objective To explore what can be learnt about the current composition of the 'global landscape' of health research and development (R&D) from data on the World Health Organization's International Clinical Trials Registry Platform (ICTRP). Methods A random 5% sample of the records of clinical trials...
| Publicado en: | Bulletin of the World Health Organization Vol. 91; no. 6; pp. 416 - 417 |
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| Autores principales: | , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
World Health Organization
Jun2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104196737&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104196737 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00429686 BUW jtl: Bulletin of the World Health Organization issn: 00429686 maglogo: N pubinfo: dt: Jun2013 vid: 91 iid: 6 pid: 437 pub: World Health Organization artinfo: ui: 104196737 89060734 10.2471/BLT.12.114454 NLM24052678 104196737 ppf: 416 ppct: 1 formats: fmt: @attributes: type: P tig: atl: Use of data from registered clinical trials to identify gaps in health research and development. aug: au: Viergever, Roderik F. Terry, Robert F. Karam, Ghassan affil: Department of Primary and Community Care, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands. sug: subj: Research, Medical Evaluation Clinical Trials Evaluation World Health Evaluation Human Random Sample Descriptive Statistics Confidence Intervals Data Analysis, Statistical Data Analysis Software P-Value Odds Ratio ab: Objective To explore what can be learnt about the current composition of the 'global landscape' of health research and development (R&D) from data on the World Health Organization's International Clinical Trials Registry Platform (ICTRP). Methods A random 5% sample of the records of clinical trials that were registered as interventional and actively recruiting was taken from the ICTRP database. Findings Overall, 2381 records of trials were investigated. Analysis of these records indicated that, for every million disability-adjusted life years (DALYs) caused by communicable, maternal, perinatal and nutritional conditions, by noncommunicable diseases, or by injuries, the ICTRP database contained an estimated 7.4, 52.4 and 6.0 trials in which these causes of burden of disease were being investigated, respectively. For every million DALYs in high-income, upper-middle-income, lower-middle-income and low-income countries, an estimated 292.7, 13.4, 3.0 and 0.8 registered trials, respectively, were recruiting in such countries. Conclusion The ICTRP constitutes a valuable resource for assessing the global distribution of clinical trials and for informing policy development for health R&D. Populations in lower-income countries receive much less attention, in terms of clinical trial research, than populations in higher-income countries. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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