Antibiotic resistance patterns in medical and surgical patients in a combined medical-surgical intensive care unit.

Purpose: Studies have found different rates of antimicrobial resistance among patients in medical and surgical intensive care units (ICUs). We studied whether these differences were a function of geography or differences in the patient populations, by comparing resistance rates among bacteria isolat...

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Published in:Journal of Critical Care Vol. 28; no. 4; pp. 347 - 352
Main Authors: Akulian, Jason A., Metersky, Mark L.
Format: research tables/charts Journal Article
Published: Elsevier B.V. 2013
Online Access:View this record in EBSCOhost
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      dt: 2013
      vid: 28
      iid: 4
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      pub: Elsevier B.V.
      place: Philadelphia, Pennsylvania
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        10.1016/j.jcrc.2012.02.006
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        104198752
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        atl: Antibiotic resistance patterns in medical and surgical patients in a combined medical-surgical intensive care unit.
      aug:
        au:
          Akulian, Jason A.
          Metersky, Mark L.
        affil: Division of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins University, Baltimore, MD 21224-6801, USA
      sug:
        subj:
          Drug Resistance, Microbial
          Surgical Patients Evaluation
          Patient Care Methods
          Intensive Care Units
          Critical Care
          Human
          Serial Publications
          Retrospective Design
          Cell Culture Techniques
          Data Collection
          Demography
          Sensitivity and Specificity
          Infection Mortality
          Critically Ill Patients Evaluation
          Academic Medical Centers
          Patient Admission Evaluation
          Methicillin-Resistant Staphylococcus Aureus
          Staphylococcal Infections Diagnosis
          Middle Age
          Male
          Female
          Pulmonary Disease, Chronic Obstructive Diagnosis
          Kidney Failure, Chronic
          Coronary Disease Diagnosis
          Culture Techniques
          Lactose
          Gram-Negative Bacterial Infections Diagnosis
          Data Analysis
          Descriptive Statistics
          Middle Aged: 45-64 years
          Male
          Female
      ab: Purpose: Studies have found different rates of antimicrobial resistance among patients in medical and surgical intensive care units (ICUs). We studied whether these differences were a function of geography or differences in the patient populations, by comparing resistance rates among bacteria isolated from a combined medical/surgical ICU. Materials and Methods: We retrospectively evaluated the results of bacterial cultures of each patient admitted to the ICU between February 2005 and September 2006. Data collection included patient demographics and culture and sensitivity results. Intensive care unit populations were compared using the Fisher exact test and the Student t test. Results: One hundred seventy-one medical and 94 surgical patients with positive cultures were studied. Organisms were grouped into 4 classes: Staphylococcus aureus, nonlactose fermenting gram-negative bacilli, Enterococcus species, and gram-negative enteric bacteria. In the 4 classes, no significant difference in antibiotic resistance was found between medical and surgical patients. Conclusion: Reported differences in resistance patterns among bacteria cultured from medical and surgical patients may be due to geographic separation of the ICUs as opposed to differences in the patient characteristics. This study suggests that ICU-specific antibiograms remain a useful tool to guide the choice of antimicrobial therapy, even in medical/surgical ICUs.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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