Humidification of Inspired Oxygen Is Increased With Pre-nasal Cannula, Compared to Intranasal Cannula.

BACKGROUND: Oxygen therapy is usually combined with a humidification device, to prevent mucosal dryness. Depending on the cannula design, oxygen can be administered pre- or intranasally (administration of oxygen in front of the nasal ostia vs cannula system inside the nasal vestibulum). The impact o...

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Publicado en:Respiratory Care Vol. 58; no. 8; pp. 1323 - 1329
Autores principales: Dellweg, Dominic, Wenze, Markus, Hoehn, Ekkehard, Bourgund, Olaf, Haidl, Peter
Formato: pictorial tables/charts Journal Article
Publicado: Mary Ann Liebert, Inc. Aug2013
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Mary Ann Liebert, Inc.
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        atl: Humidification of Inspired Oxygen Is Increased With Pre-nasal Cannula, Compared to Intranasal Cannula.
      aug:
        au:
          Dellweg, Dominic
          Wenze, Markus
          Hoehn, Ekkehard
          Bourgund, Olaf
          Haidl, Peter
        affil: Department of Pulmonology, Intensive Care, and Sleep Medicine, Fachkrankenhaus Kloster Grafschaft, Schmallenberg, Germany
      sug:
        subj:
          Nebulizers and Vaporizers Statistics and Numerical Data
          Oxygen Therapy
          Nasal Mucosa
          Pearson's Correlation Coefficient
          Post Hoc Analysis
          Descriptive Statistics
          Data Analysis Software
          Factor Analysis
          Human
      ab: BACKGROUND: Oxygen therapy is usually combined with a humidification device, to prevent mucosal dryness. Depending on the cannula design, oxygen can be administered pre- or intranasally (administration of oxygen in front of the nasal ostia vs cannula system inside the nasal vestibulum). The impact of cannula design on intra-nasal humidity, however, has not been investigated to date. OBJECTIVE: First, to develop a system, that samples air from the nasal cavity and analyzes the humidity of these samples. Second, to investigate nasal humidity during pre-nasal and intra-nasal oxygen application, with and without humidification. METHODS: We first developed and validated a sampling and analysis system to measure humidity from air samples. By means of this system we measured inspiratory air samples from 12 subjects who received nasal oxygen with an intra-nasal and pre-nasal cannula at different flows, with and without humidification. RESULTS: The sampling and analysis system showed good correlation to a standard hygrometer within the tested humidity range (r = 0.99, P < .001). In our subjects intranasal humidity dropped significantly, from 40.3 ± 8.7% to 35.3 ± 5.8%, 32 ± 5.6%, and 29.0 ± 6.8% at flows of 1, 2, and 3 L, respectively, when oxygen was given intra-nasally without humidification (P = .001, P < .001, and P < .001, respectively). We observed no significant change in airway humidity when oxygen was given pre-nasally without humidification. With the addition of humidification we observed no significant change in humidity at any flow, and independent of pre- or intranasal oxygen administration. CONCLUSIONS: Pre-nasal administration of dry oxygen achieves levels of intranasal humidity similar to those achieved by intranasal administration in combination with a bubble through humidifier. Pre-nasal oxygen simplifies application and may reduce therapy cost.
      pubtype: Academic Journal
      doctype:
        pictorial
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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