Current computed tomography techniques can detect duct of Bellini plugging but not Randall's plaques.
Objective: To assess the ability of noninvasive computed tomography (CT) scans to detect interstitial calcium phosphate deposits (Randall's plaques) and duct of Bellini plugs, which are possible stone precursor lesions.Methods: At time of percutaneous nephrolithotomy (PCNL) for stone removal, all ac...
| Publicado en: | Urology Vol. 82; no. 2; pp. 301 - 307 |
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| Autores principales: | , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Elsevier B.V.
Aug2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104201733&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104201733 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00904295 1YG jtl: Urology issn: 00904295 maglogo: N pubinfo: dt: Aug2013 vid: 82 iid: 2 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 104201733 NLM23791212 2012205276 10.1016/j.urology.2013.04.028 NLM23791212 PMC3744363 104201733 ppf: 301 ppct: 6 formats: tig: atl: Current computed tomography techniques can detect duct of Bellini plugging but not Randall's plaques. aug: au: Krambeck, Amy E Lieske, John C Li, Xujian Bergstralh, Eric J Rule, Andrew D Holmes 3rd, David McCollough, Cynthia M Vrtiska, Terri J Holmes, David 3rd affil: Department of Urology, Mayo Clinic, Rochester, MN. Electronic address: krambeck.amy@mayo.edu. sug: subj: Kidney Calculi Radiography Kidney Tubules Radiography Tomography, X-Ray Computed Adult Aged Aged, 80 and Over Phosphates Female Human Image Processing, Computer Assisted Kidney Calculi Kidney Calculi Etiology Male Middle Age Prospective Studies Sensitivity and Specificity Single-Blind Studies Young Adult Adult: 19-44 years Aged: 65+ years Aged, 80 & over Middle Aged: 45-64 years Female Male ab: Objective: To assess the ability of noninvasive computed tomography (CT) scans to detect interstitial calcium phosphate deposits (Randall's plaques) and duct of Bellini plugs, which are possible stone precursor lesions.Methods: At time of percutaneous nephrolithotomy (PCNL) for stone removal, all accessible individual papillae of 105 patients were endoscopically visualized and video recorded. Image-processing software was used to estimate the percentage of papillary surface occupied by plaque or plug in each pole (upper, middle, lower). The location of stones was also recorded. A radiologist blinded to the mapping results scored presurgical (n = 98) and postsurgical (n = 105) abdominal CT scans for the presence or absence of calcification by pole.Results: The cohort was a mean age of 56 years (range, 23-84 years). Maximum papillary surface area of each area of the kidney occupied by plug correlated with CT calcifications on pre- and postprocedure images by rank sum test. However, maximum plaque surface area did not correlate with radiographic findings (P = .10-.90 for each pole by rank sum test). Sensitivity was 81% and specificity was 69% of CT to detect plugs of at least 1% of the papillary surface area.Conclusion: Calcifications seen on current generation clinical CT scans correspond to ductal plugging involving at least 1% of the papillary surface area. Current clinical CT scan technology appears inadequate for detecting Randall's plaques. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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