Is Gender Responsible for Everything? The Relationship between Sex and Right Ventricular Remodeling in Metabolic Syndrome.

Background The aim of this study was to examine the impact of metabolic syndrome ( MS) on right ventricular ( RV) remodeling in different genders. Methods The study included 341 subjects (216 subjects with MS and 125 controls). MS was defined by the presence of ≥3 ATP- NCEP- III criteria. All subjec...

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Publicado en:Echocardiography Vol. 30; no. 7; pp. 778 - 786
Autores principales: Tadic, Marijana V., Ivanovic, Branislava A., Petrovic, Milan
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Aug2013
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2013
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Is Gender Responsible for Everything? The Relationship between Sex and Right Ventricular Remodeling in Metabolic Syndrome.
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        au:
          Tadic, Marijana V.
          Ivanovic, Branislava A.
          Petrovic, Milan
        affil: Clinical Center of Serbia Clinic for Cardiology
      sug:
        subj:
          Ventricular Remodeling
          Metabolic Syndrome X
          Sex Factors
          Human
          Male
          Female
          Echocardiography, Doppler
          Control Group
          T-Tests
          Descriptive Statistics
          Data Analysis Software
          Two-Way Analysis of Variance
          Chi Square Test
          Pearson's Correlation Coefficient
          Adult
          Middle Age
          Aged
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Background The aim of this study was to examine the impact of metabolic syndrome ( MS) on right ventricular ( RV) remodeling in different genders. Methods The study included 341 subjects (216 subjects with MS and 125 controls). MS was defined by the presence of ≥3 ATP- NCEP- III criteria. All subjects underwent complete two-dimensional echocardiography. Results RV structure, diastolic, and global function were significantly impaired in MS subjects, in both genders. The multiple regression analysis of MS parameters showed that systolic blood pressure ( BP) and waist circumference were independently associated with RV wall thickness in women, whereas the only independent predictor in men was systolic BP. The multivariate logistic regression analysis revealed that increased BP, impaired fasting glucose, and dyslipidemia were a combination of MS risk factors related with RV hypertrophy solely in women. Increased systolic BP, impaired fasting glucose, and abdominal obesity were independently associated with tricuspid E/e′ in women, whereas increased systolic BP was the only independent predictor in men. Impaired fasting glucose, abdominal obesity, and dyslipidemia were a combination of MS criteria, which was independently associated with RV diastolic dysfunction only in women. Conclusions Different parameters of MS are responsible for RV remodeling in women and men. The metabolic parameters of MS are more important for RV remodeling in women.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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