Long-Term Effect of Septal or Apical Pacing on Left and Right Ventricular Function after Permanent Pacemaker Implantation.

Background Right ventricular ( RV) pacing is associated with left ventricular ( LV) dysfunction. However, the effects of RV pacing at different sites on both LV and RV function have rarely been studied before. We want to determine whether different RV pacing sites differentially affect LV and RV def...

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Publicado en:Echocardiography Vol. 30; no. 7; pp. 812 - 820
Autores principales: Chen, Ju-Yi, Tsai, Wei-Chuan, Liu, Yen-Wen, Li, Wen-Huang, Li, Yi-Heng, Tsai, Liang-Miin, Lin, Li-Jen
Formato: diagnostic images research tables/charts Journal Article
Publicado: Wiley-Blackwell Aug2013
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Long-Term Effect of Septal or Apical Pacing on Left and Right Ventricular Function after Permanent Pacemaker Implantation.
      aug:
        au:
          Chen, Ju-Yi
          Tsai, Wei-Chuan
          Liu, Yen-Wen
          Li, Wen-Huang
          Li, Yi-Heng
          Tsai, Liang-Miin
          Lin, Li-Jen
        affil: Institute of Clinical Medicine, College of Medicine, National Cheng Kung University; Division of Cardiology, Department of Internal Medicine, National Cheng Kung University Hospital
      sug:
        subj:
          Cardiac Pacing, Artificial Methods
          Ventricular Dysfunction, Right Diagnosis
          Sick Sinus Syndrome Therapy
          Human
          Structured Interview
          Echocardiography, Doppler
          T-Tests
          Chi Square Test
          Descriptive Statistics
          Data Analysis Software
          Pretest-Posttest Control Group Design
          Male
          Female
          Aged
          Aged, 80 and Over
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Background Right ventricular ( RV) pacing is associated with left ventricular ( LV) dysfunction. However, the effects of RV pacing at different sites on both LV and RV function have rarely been studied before. We want to determine whether different RV pacing sites differentially affect LV and RV deformation by using speckle tracking echocardiography ( STE). Methods The subjects were 73 patients who had undergone dual-chamber permanent pacemaker implantation and did not have structural heart diseases. LV and RV global longitudinal strains ( GLS) were measured using STE to determine subtle changes in LV function. Twenty-three patients without pacing after pacemaker implantation served as controls; 14 and 36 patients showed apical and septal pacing, respectively. Results There were no significant intergroup demographic differences. LV biplane ejection fractions in the septal- and apical-pacing groups were significantly lower than those in the controls. The GLSLV values were similar between the control and septal-pacing groups, but they were lower in the apical-pacing group. Multivariate analysis revealed that cumulative pacing loads and apical pacing were independent factors associated with lower GLSLV values. The GLSRV values were similar between the control and apical-pacing groups; however, they were lower in the septal-pacing group. Conclusion We concluded that patients with septal pacing have significantly higher GLSLV and more modest decreases in GLSRV values than patients with apical pacing. Thus, septal pacing may be not necessarily preferable in patients without significant heart disease undergoing dual-chamber permanent pacemaker implantation.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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