Effect of congenital heart defects on language development in toddlers with Down syndrome.
Background Down syndrome ( DS, OMIM #190685) is the most commonly identified genetic form of intellectual disability with congenital heart defect ( CHD) occurring in 50% of cases. With advances in surgical techniques and an increasing lifespan, this has necessitated a greater understanding of the ne...
| Publicado en: | Journal of Intellectual Disability Research Vol. 57; no. 9; pp. 887 - 893 |
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| Autores principales: | , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Sep2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104209803&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104209803 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09642633 EUL jtl: Journal of Intellectual Disability Research issn: 09642633 maglogo: Y pubinfo: dt: Sep2013 vid: 57 iid: 9 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 104209803 89720245 10.1111/j.1365-2788.2012.01619.x NLM22998351 104209803 ppf: 887 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Effect of congenital heart defects on language development in toddlers with Down syndrome. aug: au: Visootsak, J. Hess, B. Bakeman, R. Adamson, L. B. affil: Human Genetics and Pediatrics, Emory University School of Medicine sug: subj: Heart Defects, Congenital Complications Language Development Evaluation Down Syndrome Human Georgia Child, Preschool Clinical Assessment Tools Parent-Child Relations Psychological Tests Language Tests Mann-Whitney U Test Descriptive Statistics Child, Preschool: 2-5 years ab: Background Down syndrome ( DS, OMIM #190685) is the most commonly identified genetic form of intellectual disability with congenital heart defect ( CHD) occurring in 50% of cases. With advances in surgical techniques and an increasing lifespan, this has necessitated a greater understanding of the neurodevelopmental consequences of CHDs. Herein, we explore the impact of CHD on language development in children with DS. Methods Twenty-nine children with DS were observed systematically in parent-child interactions using the Communication Play Protocol to evaluate their language use; they also completed the Mullen Scales of Early Learning and Mac Arthur Communication Development Inventory. Mean ages were 31.2 months for children with DS and CHD ( DS + CHD, n = 12) and 32.1 months for children with DS and a structurally normal heart ( DS − CHD, n = 17). Results Compared with the DS − CHD controls, the DS + CHD group revealed lower scores in multiple areas, including fine motor skills and expressive and receptive vocabulary. Whereas most differences were not statistically significant, the Communication Development Inventory word count and symbol-infused joint engagement differed significantly ( P < 0.01) and marginally ( P = 0.09) between groups. Conclusions Finding that CHDs may account for part of the variation in language delay allows us to consider the specific mechanisms underlying the impact of CHDs on language acquisition in children with DS. Conclusions from this first study on early language outcomes of children with DS + CHD may be useful for clinicians in providing developmental surveillance and early intervention programmes with specific emphasis on language therapy as part of long-term follow-up for children with DS + CHD. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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