Developing a New Simplified Method to Determine Diffusive Uptake Rates of Volatile Organic Compounds in Workplaces Based on a Fractional Factorial Designs Approach.
Exposure to organic vapors in the workplace is a source of occupational risk. Admissible exposure levels are tightly regulated and must be closely monitored. However, the complexity and slowness of the existing complete protocols to determine diffusive uptake rates through passive sampling have limi...
| Publicado en: | Journal of Occupational & Environmental Hygiene Vol. 10; no. 9; pp. 505 - 519 |
|---|---|
| Autores principales: | , , , , |
| Formato: | equations & formulas research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Sep2013
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104211418&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104211418 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15459624 V1L jtl: Journal of Occupational & Environmental Hygiene issn: 15459624 maglogo: Y pubinfo: dt: Sep2013 vid: 10 iid: 9 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 104211418 89660789 10.1080/15459624.2013.818232 NLM23927073 104211418 ppf: 505 ppct: 14 formats: fmt: @attributes: type: P tig: atl: Developing a New Simplified Method to Determine Diffusive Uptake Rates of Volatile Organic Compounds in Workplaces Based on a Fractional Factorial Designs Approach. aug: au: Estève, Williams Lhuillier, Francine Ravera, Christel Grzebyck, Michel Langlois, Eddy affil: Laboratoire de Chimie Analytique Organique, Département Métrologie des Polluants , Institut National de Recherche et de Sécurité (INRS) , Vandoeuvre , France sug: subj: Diffusion Equipment and Supplies Diffusion Evaluation Occupational Exposure Extraction and Processing Industry Human France Field Studies Factorial Design Protocols Charcoal Confidence Intervals Odds Ratio ab: Exposure to organic vapors in the workplace is a source of occupational risk. Admissible exposure levels are tightly regulated and must be closely monitored. However, the complexity and slowness of the existing complete protocols to determine diffusive uptake rates through passive sampling have limited the use of this tool despite obvious advantages. In this study, we experimentally validate two simplified protocols to determine diffusive uptake rates with passive sampling. The proposed 26-3and 26-2fractional factorial designs were validated for toluene sampling using a (Gas Adsorbent Badge for Individual Exposure) GABIE-activated charcoal sampler in a controlled atmosphere. The uptake rate for this sampler had been determined previously using a full protocol. The uptake rates for all three protocols were similar, indicating that the proposed new designs can be substituted for classical full protocols. After validation of our protocols, uptake rates for new substances used as fuel additives (methyl and ethyl tert-butyl ethers, MTBE and ETBE) were determined on the same sampler using the 26-2design. In these experiments, temperature appears to have a non-negligible influence on the uptake rates measured for these compounds. With some precautions of usage (ambient temperature below a determined limit temperature or at least exposure time ≥4 h) and storage (storage temperature = 4°C) of the sampler, the experimental diffusive uptake rates determined by this method can be used with good confidence. Field experiments confirmed the experimental results, showing good agreement between active and passive sampling using the experimentally determined uptake rates. pubtype: Academic Journal doctype: equations & formulas research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|