Systematic Review and Meta-analysis of Pharmacological Treatment of the Symptoms of Attention-Deficit/Hyperactivity Disorder in Children with Pervasive Developmental Disorders.
Many children with pervasive developmental disorders (PDD) exhibit behaviors and symptoms of attention-deficit/hyperactivity disorder (ADHD). We sought to determine the relative efficacy of medications for treating ADHD symptoms in children with PDD by identifying all double-blind, randomized, place...
| Publicado en: | Journal of Autism & Developmental Disorders Vol. 43; no. 10; pp. 2435 - 2442 |
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| Autores principales: | , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Springer Nature
Oct2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104226083&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104226083 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01623257 AUT jtl: Journal of Autism & Developmental Disorders issn: 01623257 maglogo: N pubinfo: dt: Oct2013 vid: 43 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104226083 90245031 10.1007/s10803-013-1793-z NLM23468071 104226083 ppf: 2435 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Systematic Review and Meta-analysis of Pharmacological Treatment of the Symptoms of Attention-Deficit/Hyperactivity Disorder in Children with Pervasive Developmental Disorders. aug: au: Reichow, Brian Volkmar, Fred Bloch, Michael affil: Yale School of Medicine Child Study Center, 230 South Frontage Road New Haven 06519 USA sug: subj: Attention Deficit Hyperactivity Disorder Drug Therapy Treatment Outcomes Attention Deficit Hyperactivity Disorder Symptoms Child Development Disorders, Pervasive Complications Systematic Review Human Meta Analysis Child PubMed Descriptive Statistics Models, Statistical Data Analysis Software Confidence Intervals Child: 6-12 years ab: Many children with pervasive developmental disorders (PDD) exhibit behaviors and symptoms of attention-deficit/hyperactivity disorder (ADHD). We sought to determine the relative efficacy of medications for treating ADHD symptoms in children with PDD by identifying all double-blind, randomized, placebo-controlled trials examining the efficacy of medications for treating ADHD symptoms in children with PDD. We located seven trials involving 225 children. A random effects meta-analysis of four methylphenidate trials showed methylphenidate to be effective for treating ADHD symptoms in children with PDD (ES = .67). Several adverse events were greater for children were taking methylphenidate compared to placebo. An individual trial of clonidine and two trials of atomoxetine suggest these agents may also be effective in treating ADHD symptoms in children with PDD. pubtype: Academic Journal doctype: meta analysis research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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