A Supervised Learning Approach for Crohn's Disease Detection Using Higher-Order Image Statistics and a Novel Shape Asymmetry Measure.

Increasing incidence of Crohn's disease (CD) in the Western world has made its accurate diagnosis an important medical challenge. The current reference standard for diagnosis, colonoscopy, is time-consuming and invasive while magnetic resonance imaging (MRI) has emerged as the preferred noninvasive...

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Publicado en:Journal of Digital Imaging Vol. 26; no. 5; pp. 920 - 932
Autores principales: Mahapatra, Dwarikanath, Schueffler, Peter, Tielbeek, Jeroen, Buhmann, Joachim, Vos, Franciscus
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Oct2013
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2013
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      pub: Springer Nature
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          Mahapatra, Dwarikanath
          Schueffler, Peter
          Tielbeek, Jeroen
          Buhmann, Joachim
          Vos, Franciscus
        affil: Department of Computer Science, ETH Zurich, Zurich Switzerland
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        subj:
          Crohn Disease Diagnosis
          Magnetic Resonance Imaging
          Image Interpretation, Computer Assisted
          Human
          Female
          Male
          Adult
          Middle Age
          Aged
          Data Analysis, Statistical
          ROC Curve
          T-Tests
          P-Value
          Funding Source
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Female
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      ab: Increasing incidence of Crohn's disease (CD) in the Western world has made its accurate diagnosis an important medical challenge. The current reference standard for diagnosis, colonoscopy, is time-consuming and invasive while magnetic resonance imaging (MRI) has emerged as the preferred noninvasive procedure over colonoscopy. Current MRI approaches assess rate of contrast enhancement and bowel wall thickness, and rely on extensive manual segmentation for accurate analysis. We propose a supervised learning method for the identification and localization of regions in abdominal magnetic resonance images that have been affected by CD. Low-level features like intensity and texture are used with shape asymmetry information to distinguish between diseased and normal regions. Particular emphasis is laid on a novel entropy-based shape asymmetry method and higher-order statistics like skewness and kurtosis. Multi-scale feature extraction renders the method robust. Experiments on real patient data show that our features achieve a high level of accuracy and perform better than two competing methods.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
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        Journal Article
      ougenre: Article
    language: English
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