Adrenal Gland Abnormality Detection Using Random Forest Classification.

Adrenal abnormalities are commonly identified on computed tomography (CT) and are seen in at least 5 % of CT examinations of the thorax and abdomen. Previous studies have suggested that evaluation of Hounsfield units within a region of interest or a histogram analysis of a region of interest can be...

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Publicado en:Journal of Digital Imaging Vol. 26; no. 5; pp. 891 - 898
Autores principales: Saiprasad, Ganesh, Chang, Chein-I, Safdar, Nabile, Saenz, Naomi, Siegel, Eliot
Formato: equations & formulas pictorial tables/charts Journal Article
Publicado: Springer Nature Oct2013
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2013
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      pub: Springer Nature
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        atl: Adrenal Gland Abnormality Detection Using Random Forest Classification.
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          Saiprasad, Ganesh
          Chang, Chein-I
          Safdar, Nabile
          Saenz, Naomi
          Siegel, Eliot
        affil: Department of Electrical Engineering, University of Maryland Baltimore County, 1000 Hilltop Circle Baltimore 21250 USA
      sug:
        subj:
          Tomography, X-Ray Computed
          Diagnosis, Computer Assisted Methods
          Adrenal Gland Diseases Diagnosis
          Classification Methods
          Algorithms
      ab: Adrenal abnormalities are commonly identified on computed tomography (CT) and are seen in at least 5 % of CT examinations of the thorax and abdomen. Previous studies have suggested that evaluation of Hounsfield units within a region of interest or a histogram analysis of a region of interest can be used to determine the likelihood that an adrenal gland is abnormal. However, the selection of a region of interest can be arbitrary and operator dependent. We hypothesize that segmenting the entire adrenal gland automatically without any human intervention and then performing a histogram analysis can accurately detect adrenal abnormality. We use the random forest classification framework to automatically perform a pixel-wise classification of an entire CT volume (abdomen and pelvis) into three classes namely right adrenal, left adrenal, and background. Once we obtain this classification, we perform histogram analysis to detect adrenal abnormality. The combination of these methods resulted in a sensitivity and specificity of 80 and 90 %, respectively, when analyzing 20 adrenal glands seen on volumetric CT datasets for abnormality.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        pictorial
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        Journal Article
      ougenre: Article
    language: English
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