Artificial neural network classification of pharyngeal high-resolution manometry with impedance data.

Objectives/hypothesis: To use classification algorithms to classify swallows as safe, penetration, or aspiration based on measurements obtained from pharyngeal high-resolution manometry (HRM) with impedance.Study Design: Case series evaluating new method of data analysis.Methods: Multilayer perceptr...

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Publicado en:Laryngoscope Vol. 123; no. 3; pp. 713 - 721
Autores principales: Hoffman, Matthew R, Mielens, Jason D, Omari, Taher I, Rommel, Nathalie, Jiang, Jack J, McCulloch, Timothy M
Formato: research Journal Article
Publicado: Wiley-Blackwell Mar2013
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Mar2013
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Artificial neural network classification of pharyngeal high-resolution manometry with impedance data.
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        au:
          Hoffman, Matthew R
          Mielens, Jason D
          Omari, Taher I
          Rommel, Nathalie
          Jiang, Jack J
          McCulloch, Timothy M
        affil: Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, U.S.A.
      sug:
        subj:
          Algorithms
          Deglutition Physiology
          Manometry Classification
          Neural Networks (Computer)
          Adult
          Aged
          Aged, 80 and Over
          Female
          Male
          Middle Age
          ROC Curve
          Funding Source
          Human
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
          Female
          Male
      ab: Objectives/hypothesis: To use classification algorithms to classify swallows as safe, penetration, or aspiration based on measurements obtained from pharyngeal high-resolution manometry (HRM) with impedance.Study Design: Case series evaluating new method of data analysis.Methods: Multilayer perceptron, an artificial neural network (ANN), was evaluated for its ability to classify swallows as safe, penetration, or aspiration. Data were collected from 25 disordered subjects swallowing 5- or 10-mL boluses. Following extraction of relevant parameters, a subset of the data was used to train the models, and the remaining swallows were then independently classified by the ANN.Results: A classification accuracy of 89.4 ± 2.4% was achieved when including all parameters. Including only manometry-related parameters yielded a classification accuracy of 85.0 ± 6.0%, whereas including only impedance-related parameters yielded a classification accuracy of 76.0 ± 4.9%. Receiver operating characteristic analysis yielded areas under the curve of 0.8912 for safe, 0.8187 for aspiration, and 0.8014 for penetration.Conclusions: Classification models show high accuracy in classifying swallows from dysphagic patients as safe or unsafe. HRM-impedance with ANN represents one method that could be used clinically to screen for patients at risk for penetration or aspiration.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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