Acute and Chronic Effects of Smoking on Myocardial Function in Healthy Heavy Smokers: A Study of Doppler Flow, Doppler Tissue Velocity, and Two-Dimensional Speckle Tracking Echocardiography.

Background: The purpose of the study was to evaluate the acute and chronic effect of smoking on left ventricular function in healthy heavy smokers by conventional Doppler flow, tissue Doppler, and two-dimensional speckle tracking echocardiography (2 D- STE). Methods: Echocardiograms were performed i...

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Published in:Echocardiography Vol. 30; no. 3; pp. 285 - 293
Main Authors: Farsalinos, Konstantinos, Tsiapras, Dimitrios, Kyrzopoulos, Stamatis, Voudris, Vassilis
Format: diagnostic images research tables/charts tracings Journal Article
Published: Wiley-Blackwell Mar2013
Online Access:View this record in EBSCOhost
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      dt: Mar2013
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Acute and Chronic Effects of Smoking on Myocardial Function in Healthy Heavy Smokers: A Study of Doppler Flow, Doppler Tissue Velocity, and Two-Dimensional Speckle Tracking Echocardiography.
      aug:
        au:
          Farsalinos, Konstantinos
          Tsiapras, Dimitrios
          Kyrzopoulos, Stamatis
          Voudris, Vassilis
        affil: 2nd department of Cardiology, Onassis Cardiac Surgery Center
      sug:
        subj:
          Smoking Complications
          Heart Ventricle, Left Physiology
          Echocardiography Methods
          Echocardiography, Doppler Methods
          Human
          Adult
          Descriptive Statistics
          Adolescence
          Middle Age
          T-Tests
          Chi Square Test
          Interrater Reliability
          Intrarater Reliability
          Data Analysis Software
          Male
          Female
          Adult: 19-44 years
          Adolescent: 13-18 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Background: The purpose of the study was to evaluate the acute and chronic effect of smoking on left ventricular function in healthy heavy smokers by conventional Doppler flow, tissue Doppler, and two-dimensional speckle tracking echocardiography (2 D- STE). Methods: Echocardiograms were performed in 42 healthy heavy (>20 cigarettes/day) smokers (age 34 ± 5 years), before (group SM-1), 15 minutes ( SM-2) and 30 minutes ( SM-3) after starting smoking 2 cigarettes. Nonsmokers (n = 41, age 33 ± 4 years) served as controls. Transmitral flow, isovolumetric relaxation time ( IVRT), and myocardial performance index ( MPI) were measured. Tissue velocity measurements were averaged from lateral and septal mitral annulus. Longitudinal strain ( GS), systolic ( SRs), early diastolic ( SRe), late diastolic ( SRa), and isovolumetric relaxation ( SRivr) strain rate were measured. The percent change in strain from end-systole to the first one-third of diastole ( SI- DI = [( GS − strain at one-third diastole)/ GS] × 100) was also measured. Results: IVRT and MPI were increased and early diastolic mitral annular velocity was decreased in SM-2; they returned to baseline in SM-3. There was no difference in GS and SRs. SRe and SRivr were reduced in SM-1 (P < 0.05), and remained significantly reduced in SM-2 and SM-3. SI- DI was lower in SM-1 (P = 0.011) and was further reduced in SM-2 and SM-3 (P < 0.001). Conclusion: Acute and chronic smoking inhalation has adverse effects on myocardial function in healthy heavy smokers. 2D- STE is able to detect both baseline differences and late acute effects of smoking.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        tracings
        Journal Article
      ougenre: Article
    language: English
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