Mammographic Image Denoising and Enhancement Using the Anscombe Transformation, Adaptive Wiener Filtering, and the Modulation Transfer Function.

A new restoration methodology is proposed to enhance mammographic images through the improvement of contrast features and the simultaneous suppression of noise. Denoising is performed in the first step using the Anscombe transformation to convert the signal-dependent quantum noise into an approximat...

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Publicado en:Journal of Digital Imaging Vol. 26; no. 2; pp. 183 - 198
Autores principales: Romualdo, Larissa, Vieira, Marcelo, Schiabel, Homero, Mascarenhas, Nelson, Borges, Lucas
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Apr2013
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2013
      vid: 26
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      pub: Springer Nature
      place: New York, New York
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        atl: Mammographic Image Denoising and Enhancement Using the Anscombe Transformation, Adaptive Wiener Filtering, and the Modulation Transfer Function.
      aug:
        au:
          Romualdo, Larissa
          Vieira, Marcelo
          Schiabel, Homero
          Mascarenhas, Nelson
          Borges, Lucas
        affil: Electrical Engineering Department, University of São Paulo, USP, Av. Trabalhador São-Carlense, 400 São Carlos Brazil
      sug:
        subj:
          Mammography
          Breast Neoplasms Diagnosis
          Breast Radiography
          Breast Neoplasms Radiography
          Radiographic Magnification Methods
          Diagnosis, Computer Assisted
          Algorithms
          Radiography, Computed
          Calcinosis Diagnosis
          Evaluation Research
          Paired T-Tests
          P-Value
          Sensitivity and Specificity
          ROC Curve
          Human
          Funding Source
      ab: A new restoration methodology is proposed to enhance mammographic images through the improvement of contrast features and the simultaneous suppression of noise. Denoising is performed in the first step using the Anscombe transformation to convert the signal-dependent quantum noise into an approximately signal-independent Gaussian additive noise. In the Anscombe domain, noise is filtered through an adaptive Wiener filter, whose parameters are obtained by considering local image statistics. In the second step, a filter based on the modulation transfer function of the imaging system in the whole radiation field is applied for image enhancement. This methodology can be used as a preprocessing module for computer-aided detection (CAD) systems to improve the performance of breast cancer screening. A preliminary assessment of the restoration algorithm was performed using synthetic images with different levels of quantum noise. Afterward, we evaluated the effect of the preprocessing on the performance of a previously developed CAD system for clustered microcalcification detection in mammographic images. The results from the synthetic images showed an increase of up to 11.5 dB ( p = 0.002) in the peak signal-to-noise ratio. Moreover, the mean structural similarity index increased up to 8.3 % ( p < 0.001). Regarding CAD performance, the results suggested that the preprocessing increased the detectability of microcalcifications in mammographic images without increasing the false-positive rates. Receiver operating characteristic analysis revealed an average increase of 14.1 % ( p = 0.01) in overall CAD performance when restored image sets were used.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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