First-pass contrast-enhanced renal MRA at 7 Tesla: initial results.

Objective: The aim of this study was to assess the feasibility of first-pass contrast-enhanced renal MR angiography (MRA) at 7 T.Methods: In vivo first-pass contrast-enhanced high-field examinations were obtained in eight healthy subjects on a 7-T whole-body MRI. A custom-built body transmit/receive...

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Publicado en:European Radiology Vol. 23; no. 4; pp. 1059 - 1067
Autores principales: Umutlu, L, Maderwald, S, Kinner, S, Kraff, O, Bitz, A K, Orzada, S, Johst, S, Wrede, K, Forsting, M, Ladd, M E, Lauenstein, T C, Quick, H H
Formato: research Journal Article
Publicado: Springer Nature Apr2013
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2013
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00330-012-2666-0
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        atl: First-pass contrast-enhanced renal MRA at 7 Tesla: initial results.
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        au:
          Umutlu, L
          Maderwald, S
          Kinner, S
          Kraff, O
          Bitz, A K
          Orzada, S
          Johst, S
          Wrede, K
          Forsting, M
          Ladd, M E
          Lauenstein, T C
          Quick, H H
        affil: Erwin L. Hahn Institute for Magnetic Resonance Imaging, University Duisburg-Essen, Arendahls Wiese 199, 45141, Essen, Germany, Lale.Umutlu@uk-essen.de.
      sug:
        subj:
          Algorithms
          Image Enhancement Methods
          Image Interpretation, Computer Assisted Methods
          Magnetic Resonance Angiography Methods
          Organometallic Compounds Diagnostic Use
          Renal Artery Anatomy and Histology
          Adult
          Contrast Media
          Female
          Human
          Male
          Pilot Studies
          Reproducibility of Results
          Sensitivity and Specificity
          Adult: 19-44 years
          Female
          Male
      ab: Objective: The aim of this study was to assess the feasibility of first-pass contrast-enhanced renal MR angiography (MRA) at 7 T.Methods: In vivo first-pass contrast-enhanced high-field examinations were obtained in eight healthy subjects on a 7-T whole-body MRI. A custom-built body transmit/receive radiofrequency (RF) coil and RF system suitable for RF shimming were used for image acquisition. For dynamic imaging, gadobutrol was injected intravenously and coronal unenhanced, arterial and venous data sets using a T1-weighted spoiled gradient-echo sequence were obtained. Qualitative image analysis and assessment of artefact impairment were performed by two senior radiologists using a five-point scale (5 = excellent, 1 = non-diagnostic). SNR and CNR of the perirenal abdominal aorta and both main renal arteries were assessed.Results: Qualitative image evaluation revealed overall high-quality delineation of all assessed segments of the unenhanced arterial vasculature (meanunenhanced 4.13). Nevertheless, the application of contrast agent revealed an improvement in vessel delineation of all the vessel segments assessed, confirmed by qualitative (meanunenhanced 4.13 to meancontrast-enhanced 4.85) and quantitative analysis (SNR meanunenhanced 64.3 to meancontrast-enhanced 98.4).Conclusion: This study demonstrates the feasibility and current constraints of ultra-high-field contrast-enhanced renal MRA relative to unenhanced MRA.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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