The value of apparent diffusion coefficient in the assessment of cervical cancer.
Objectives: To evaluate the potential value of apparent diffusion coefficient (ADC) measurement in the assessment of cervical cancer.Methods: One hundred twelve patients with cervical cancer and 67 control subjects underwent diffusion-weighted imaging (DWI) in addition to routine MR imaging at 3.0-T...
| Published in: | European Radiology Vol. 23; no. 4; pp. 1050 - 1059 |
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| Main Authors: | , , , , , |
| Format: | research Journal Article |
| Published: |
Springer Nature
Apr2013
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104252370&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104252370 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Apr2013 vid: 23 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104252370 NLM23179520 2012048177 10.1007/s00330-012-2681-1 NLM23179520 104252370 ppf: 1050 ppct: 9 formats: fmt: @attributes: type: P tig: atl: The value of apparent diffusion coefficient in the assessment of cervical cancer. aug: au: Kuang, Fei Ren, Jing Zhong, Qun Liyuan, Fu Huan, Yi Chen, Ziqian affil: Department of Radiology, The 174th Hospital of Chinese PLA, No 96, Wen Yuan Road, Xiamen, Fujian Province, 361003, China. sug: subj: Algorithms Magnetic Resonance Imaging Methods Image Enhancement Methods Image Interpretation, Computer Assisted Methods Cervix Neoplasms Pathology Adult Aged Female Human Middle Age Reproducibility of Results Sensitivity and Specificity Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female ab: Objectives: To evaluate the potential value of apparent diffusion coefficient (ADC) measurement in the assessment of cervical cancer.Methods: One hundred twelve patients with cervical cancer and 67 control subjects underwent diffusion-weighted imaging (DWI) in addition to routine MR imaging at 3.0-T MRI before therapy. All ADCs were calculated from b = 0, 600 s/mm(2) and b = 0, 1,000 s/mm(2).Results: The ADCs of cervical cancer were significantly lower than those of normal cervix for both ADC maps. There was a statistically significant difference between the ADCs of well-/moderately differentiated (G1/2) tumours and poorly differentiated (G3) tumours, between the ADCs of squamous cell carcinoma and adenocarcinoma, between the pretherapy ADCs of tumour recurrence or metastasis and tumour free patients after radical hysterectomy for both ADC maps. There was no significant difference among the ADCs of cervical cancer when divided by other features (FIGO, lymph node status, tumour size and age groups) for both ADC maps.Conclusion: ADC values were reliable for differentiating cervical cancer from normal cervix with high diagnostic accuracy. The ADCs can be used to indicate the degree and histological type of cervical cancer, although there is some overlap. G3 tumours and lower ADCs may indicate poor prognosis. The diagnostic accuracy was equal for both ADC maps. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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