Autism Traits in Individuals with Agenesis of the Corpus Callosum.
Autism spectrum disorders (ASD) have numerous etiologies, including structural brain malformations such as agenesis of the corpus callosum (AgCC). We sought to directly measure the occurrence of autism traits in a cohort of individuals with AgCC and to investigate the neural underpinnings of this as...
| Publicado en: | Journal of Autism & Developmental Disorders Vol. 43; no. 5; pp. 1106 - 1119 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Springer Nature
May2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104268035&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104268035 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01623257 AUT jtl: Journal of Autism & Developmental Disorders issn: 01623257 maglogo: N pubinfo: dt: May2013 vid: 43 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104268035 86879240 10.1007/s10803-012-1653-2 NLM23054201 104268035 ppf: 1106 ppct: 13 formats: fmt: @attributes: type: P tig: atl: Autism Traits in Individuals with Agenesis of the Corpus Callosum. aug: au: Lau, Yolanda Hinkley, Leighton Bukshpun, Polina Strominger, Zoe Wakahiro, Mari Baron-Cohen, Simon Allison, Carrie Auyeung, Bonnie Jeremy, Rita Nagarajan, Srikantan Sherr, Elliott Marco, Elysa affil: School of Medicine, University of California, San Francisco, 513 Parnassus Avenue San Francisco 94143 USA sug: subj: Autism Spectrum Disorder Pathology Agenesis of Corpus Callosum Pathology Human Descriptive Statistics Child Adolescence Adult Clinical Assessment Tools California Academic Medical Centers Fisher's Exact Test Chi Square Test Child, Preschool Middle Age Aged Male Female Magnetic Resonance Imaging T-Tests Post Hoc Analysis Pearson's Correlation Coefficient Data Analysis Software Funding Source Child: 6-12 years Adolescent: 13-18 years Adult: 19-44 years Child, Preschool: 2-5 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Autism spectrum disorders (ASD) have numerous etiologies, including structural brain malformations such as agenesis of the corpus callosum (AgCC). We sought to directly measure the occurrence of autism traits in a cohort of individuals with AgCC and to investigate the neural underpinnings of this association. We screened a large AgCC cohort (n = 106) with the Autism Spectrum Quotient (AQ) and found that 45 % of children, 35 % of adolescents, and 18 % of adults exceeded the predetermined autism-screening cut-off. Interestingly, performance on the AQ's imagination domain was inversely correlated with magnetoencephalography measures of resting-state functional connectivity in the right superior temporal gyrus. Individuals with AgCC should be screened for ASD and disorders of the corpus callosum should be considered in autism diagnostic evaluations as well. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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