Capability of differentiating smokers with normal pulmonary function from COPD patients: a comparison of CT pulmonary volume analysis and MR perfusion imaging.
Objective: To compare CT volume analysis with MR perfusion imaging in differentiating smokers with normal pulmonary function (controls) from COPD patients.Methods: Sixty-two COPD patients and 17 controls were included. The total lung volume (TLV), total emphysema volume (TEV) and emphysema index (EI...
| Publicado en: | European Radiology Vol. 23; no. 5; pp. 1234 - 1242 |
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| Autores principales: | , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
May2013
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=104269997&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 104269997 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: May2013 vid: 23 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 104269997 86879536 NLM23263604 2012081840 10.1007/s00330-012-2729-2 NLM23263604 104269997 ppf: 1234 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Capability of differentiating smokers with normal pulmonary function from COPD patients: a comparison of CT pulmonary volume analysis and MR perfusion imaging. aug: au: Fan, Li Xia, Yi Guan, Yu Yu, Hong Zhang, Tie-Feng Liu, Shi-Yuan Li, Bing affil: Department of Radiology, Changzheng Hospital of the Second Military Medical University, No. 415 Fengyang Road, Shanghai, 200003, China. sug: subj: Lung Radiography Lung Volume Measurements Methods Magnetic Resonance Imaging Methods Perfusion Imaging Methods Pulmonary Disease, Chronic Obstructive Radiography Smoking Tomography, X-Ray Computed Methods Adult Aged Diagnosis, Differential Female Human Male Middle Age Reproducibility of Results Sensitivity and Specificity Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Objective: To compare CT volume analysis with MR perfusion imaging in differentiating smokers with normal pulmonary function (controls) from COPD patients.Methods: Sixty-two COPD patients and 17 controls were included. The total lung volume (TLV), total emphysema volume (TEV) and emphysema index (EI) were quantified by CT. MR perfusion evaluated positive enhancement integral (PEI), maximum slope of increase (MSI), maximum slope of decrease (MSD), signal enhancement ratio (SER) and signal intensity ratio (RSI) of perfusion defects to normal lung.Results: There were 19 class I, 17 class II, 14 class III and 12 class IV COPD patients. No differences were observed in TLV, TEV and EI between control and class I COPD. The control was different from class II, III and IV COPD in TEV and EI. The control was different from each class of COPD in RSI, MSI, PEI and MSD. Differences were found in RSI between class I and III, I and IV, and II and IV COPD. Amongst controls, MR detected perfusion defects more frequently than CT detected emphysema.Conclusions: Compared with CT, MR perfusion imaging shows higher potential to distinguish controls from mild COPD and appears more sensitive in identifying abnormalities amongst smokers with normal pulmonary function (controls).Key Points: • Detailed information is needed to diagnose chronic obstructive pulmonary disease. • High-resolution CT provides detailed anatomical and quantitative information. • Magnetic resonance imaging is demonstrating increasing potential in pulmonary function imaging. • MR perfusion can distinguish mild COPD patients from controls. • MRI appears more sensitive than CT in identifying early abnormalities amongst controls. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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