Recovery of chemical estimates by field inhomogeneity neighborhood error detection (REFINED): fat/water separation at 7 tesla.

Purpose: To reduce swaps in fat-water separation methods, a particular issue on 7 Tesla (T) small animal scanners due to field inhomogeneity, using image postprocessing innovations that detect and correct errors in the B0 field map.Materials and Methods: Fat-water decompositions and B0 field maps we...

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Publicado en:Journal of Magnetic Resonance Imaging Vol. 37; no. 5; pp. 1247 - 1254
Autores principales: Narayan, Sreenath, Kalhan, Satish C, Wilson, David L
Formato: research Journal Article
Publicado: Wiley-Blackwell May2013
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2013
      vid: 37
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      pub: Wiley-Blackwell
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        10.1002/jmri.23826
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        atl: Recovery of chemical estimates by field inhomogeneity neighborhood error detection (REFINED): fat/water separation at 7 tesla.
      aug:
        au:
          Narayan, Sreenath
          Kalhan, Satish C
          Wilson, David L
        affil: Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA. spn5@case.edu.
      sug:
        subj:
          Adipose Tissue Distribution Physiology
          Adipose Tissue Anatomy and Histology
          Adipose Tissue Physiology
          Artifacts
          Body Water
          Image Enhancement Methods
          Magnetic Resonance Imaging
          Algorithms
          Animal Studies
          Diagnostic Imaging
          Diagnostic Imaging Methods
          Magnetic Resonance Imaging Methods
          Mice
          Reproducibility of Results
          Sensitivity and Specificity
      ab: Purpose: To reduce swaps in fat-water separation methods, a particular issue on 7 Tesla (T) small animal scanners due to field inhomogeneity, using image postprocessing innovations that detect and correct errors in the B0 field map.Materials and Methods: Fat-water decompositions and B0 field maps were computed for images of mice acquired on a 7T Bruker BioSpec scanner, using a computationally efficient method for solving the Markov Random Field formulation of the multi-point Dixon model. The B0 field maps were processed with a novel hole-filling method, based on edge strength between regions, and a novel k-means method, based on field-map intensities, which were iteratively applied to automatically detect and reinitialize error regions in the B0 field maps. Errors were manually assessed in the B0 field maps and chemical parameter maps both before and after error correction.Results: Partial swaps were found in 6% of images when processed with FLAWLESS. After REFINED correction, only 0.7% of images contained partial swaps, resulting in an 88% decrease in error rate. Complete swaps were not problematic.Conclusion: Ex post facto error correction is a viable supplement to a priori techniques for producing globally smooth B0 field maps, without partial swaps. With our processing pipeline, it is possible to process image volumes rapidly, robustly, and almost automatically.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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