Evaluation of limited sampling models for prediction of oral midazolam AUC for CYP3A phenotyping and drug interaction studies.
Background : The area under the concentration-time curve (AUC) after oral midazolam administration is commonly used for cytochrome P450 (CYP) 3A phenotyping studies. The aim of this investigation was to evaluate a limited sampling strategy for the prediction of AUC with oral midazolam. Methods: A to...
| Publicado en: | European Journal of Clinical Pharmacology Vol. 69; no. 5; pp. 1127 - 1135 |
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| Autores principales: | , |
| Formato: | equations & formulas research tables/charts Journal Article |
| Publicado: |
Springer Nature
May2013
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| Acceso en línea: | Ver este registro en EBSCOhost |