Properties of Noise in Positron Emission Tomography Images Reconstructed with Filtered-Backprojection and Row-Action Maximum Likelihood Algorithm.

Noise levels observed in positron emission tomography (PET) images complicate their geometric interpretation. Post-processing techniques aimed at noise reduction may be employed to overcome this problem. The detailed characteristics of the noise affecting PET images are, however, often not well know...

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Publicado en:Journal of Digital Imaging Vol. 26; no. 3; pp. 447 - 457
Autores principales: Teymurazyan, A., Riauka, T., Jans, H.-S., Robinson, D.
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Jun2013
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2013
      vid: 26
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-012-9511-5
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        atl: Properties of Noise in Positron Emission Tomography Images Reconstructed with Filtered-Backprojection and Row-Action Maximum Likelihood Algorithm.
      aug:
        au:
          Teymurazyan, A.
          Riauka, T.
          Jans, H.-S.
          Robinson, D.
      sug:
        subj:
          Tomography, Emission-Computed
          Radiographic Image Enhancement Methods
          Radiographic Image Interpretation, Computer-Assisted
          Phantoms, Imaging
          Statistics
          Evaluation Research
          Poisson Distribution
          Goodness of Fit Chi Square Test
          Human
      ab: Noise levels observed in positron emission tomography (PET) images complicate their geometric interpretation. Post-processing techniques aimed at noise reduction may be employed to overcome this problem. The detailed characteristics of the noise affecting PET images are, however, often not well known. Typically, it is assumed that overall the noise may be characterized as Gaussian. Other PET-imaging-related studies have been specifically aimed at the reduction of noise represented by a Poisson or mixed Poisson + Gaussian model. The effectiveness of any approach to noise reduction greatly depends on a proper quantification of the characteristics of the noise present. This work examines the statistical properties of noise in PET images acquired with a GEMINI PET/CT scanner. Noise measurements have been performed with a cylindrical phantom injected with C and well mixed to provide a uniform activity distribution. Images were acquired using standard clinical protocols and reconstructed with filtered-backprojection (FBP) and row-action maximum likelihood algorithm (RAMLA). Statistical properties of the acquired data were evaluated and compared to five noise models (Poisson, normal, negative binomial, log-normal, and gamma). Histograms of the experimental data were used to calculate cumulative distribution functions and produce maximum likelihood estimates for the parameters of the model distributions. Results obtained confirm the poor representation of both RAMLA- and FBP-reconstructed PET data by the Poisson distribution. We demonstrate that the noise in RAMLA-reconstructed PET images is very well characterized by gamma distribution followed closely by normal distribution, while FBP produces comparable conformity with both normal and gamma statistics.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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