1Click1View: interactive visualization methodology for RNAi cell-based microscopic screening.

Technological advancements are constantly increasing the size and complexity of data resulting from large-scale RNA interference screens. This fact has led biologists to ask complex questions, which the existing, fully automated analyses are often not adequate to answer. We present a concept of 1Cli...

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Publicado en:BioMed Research International Vol. 2013; pp. 156932 - 156933
Autores principales: Zwolinski, Lukasz, Kozak, Marta, Kozak, Karol
Formato: Journal Article
Publicado: Wiley-Blackwell 2013
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2013
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      pub: Wiley-Blackwell
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        atl: 1Click1View: interactive visualization methodology for RNAi cell-based microscopic screening.
      aug:
        au:
          Zwolinski, Lukasz
          Kozak, Marta
          Kozak, Karol
        affil: Nauru, LTD., Breslau, Poland.
      sug:
        subj:
          Image Processing, Computer Assisted
          Genes
          Software
          Animals
      ab: Technological advancements are constantly increasing the size and complexity of data resulting from large-scale RNA interference screens. This fact has led biologists to ask complex questions, which the existing, fully automated analyses are often not adequate to answer. We present a concept of 1Click1View (1C1V) as a methodology for interactive analytic software tools. 1C1V can be applied for two-dimensional visualization of image-based screening data sets from High Content Screening (HCS). Through an easy-to-use interface, one-click, one-view concept, and workflow based architecture, visualization method facilitates the linking of image data with numeric data. Such method utilizes state-of-the-art interactive visualization tools optimized for fast visualization of large scale image data sets. We demonstrate our method on an HCS dataset consisting of multiple cell features from two screening assays.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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